Protein Alignment Cyp4p2 and cyp-13A11

DIOPT Version :10

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_499704.1
• Gene: cyp-13A11 / 184472
• WormBaseID: WBGene00008809
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 586
• Identity: 121/586 - (20%)
• Similarity: 215/586 - (36%)
• Gaps: 165/586 - (28%)

  Fly     2 MICLLWISVAILVVIH-----WIYKVNKDYNILAFFARRVQTKDGKPLDSLVPMIKGRTVFANCF 61
            ||.||::..:::.::.     |.|            .||..          :|..:|.....:..
 Worm     1 MIILLFVVSSVVGIVSYYFWTWTY------------WRRCG----------IPGPQGYPFLGSAL 43

  Fly    62 DLLGKDTDQVFTHLRQLAKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITKGVIYNF---- 122
            |::..: :..|..|::.....|..|          .:.:......:::..|||.:..:..:
 Worm    44 DMMDHE-NPPFLQLKKWTSQYGKVY----------GITEGLLRTLVISDTNLIHEVFVKQYDNFY 97

  Fly   123 ---LHPF-------LRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQ---EIFIAESLKFVSQFQ 174
               |:|.       .|..:.:|...:|...|::...||..:.|.:.|   |....|.|:.:.|..
 Worm    98 GRNLNPIQGDPNREKRVTLFSAQGHRWKRLRTIANPTFSSNNLRKIQVTVEDSALELLRHIEQHT 162

  Fly   175 GQNEVVVSLKDRISRFTLNSICETAMGIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDCV 239
            ...: .:.:.:....||::.|...||| :.|.:..|                    |||.  .|.
 Worm   163 AGGK-AIDVLEYFQEFTMDVIGRIAMG-QPDSLMFK--------------------NPLL--PCA 203

  Fly   240 YNMFTGHKYNAAL---------------KVVHEFSR-------EIIAKRRVLLEEELENRRATQT 282
            .::|  .|...||               |||..|:.       :|:.:....:|:.::.|.|.:.
 Worm   204 RDVF--GKPRTALFLSGILFPWIGPMIRKVVFYFTNVFNNPAAQIMYQTANAVEQRIKQRMAEEK 266

  Fly   283 A------------------DDDICVIRKKRFAMLDTLICAE--KDGLIDDIGISEEVDTLMAEGY 327
            |                  .||:.:...:.|......:..:  ||.::....:      .:..|:
 Worm   267 AGIDPGEPQDFIDLFLDAKSDDMELENNEDFTKAGVKVTRQLTKDEVVGQCFV------FLIAGF 325

  Fly   328 DTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSNLNLSQLSKLNYLGYFIKETMRLYPSIP 392
            |||::.|.:....::.:...|:...:||.....|  ..:...|||||.|:...||||:|:||
 Worm   326 DTTALSLSYSSFLLATHPKAQKKLQEEIDRECAD--PEVTFDQLSKLKYMECVIKETLRMYP--- 385

  Fly   393 IMG-----RQTLQETELENGLILPKRSQINIHVFDIHRNPKYW-ESPEEFRPERFLPQNCLKRHP 451
             :|     |:.::.|::.| ..:.|...|....:.:|.:...| |..|||:|||:...:   .|.
 Worm   386 -LGALANSRRCMRSTKIGN-YEIEKGVDILCDTWTLHYDKSIWGEDAEEFKPERWESGD---EHF 445

  Fly   452 Y---AYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQVGITLRFKNKIKVK 513
            |   .||||..|.|.|||.:.|..|.|.|:..||:.:                 ||...||.::.
 Worm   446 YQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKY-----------------TLEVCNKTQIP 493

  Fly   514 L 514
            |
 Worm   494 L 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	CYP4	83..512	CDD:410721	107/496 (22%)
cyp-13A11	NP_499704.1	CYP3A-like	62..506	CDD:410678	108/502 (22%)