Protein Alignment Cyp4p2 and Cyp3a62

DIOPT Version :10

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 534
• Identity: 117/534 - (21%)
• Similarity: 230/534 - (43%)
• Gaps: 96/534 - (17%)

  Fly     7 WISVAILVVIHWIYKVNKDYNILAFFARRVQTKDGKPLDSLVPMIKGRTVFANCFDLLGKDTDQV 71
            |:.:|.::|:.::|..:...|.     :::.....|||..:..::..|..|.. ||
  Rat    12 WMLLATILVLLYLYGTSTHGNF-----KKLGISGPKPLPFVGNILAYRHGFWE-FD--------- 61

  Fly    72 FTHLRQLAKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITKGVIYNFLHPF---------- 126
                |...|..||.:     ||     .:.......:..|::|...::......|
  Rat    62 ----RHCHKKYGDIW-----GF-----YEGRQPILAITDPDIIKTVLVKECYSTFTNRRSFGPAG 112

  Fly   127 -LRTGVLTATEKKWHTRRSMLTRTF-------HLDILNQFQEIFIAESLKFVSQFQGQNEVVVSL 183
             |:..:..:.:::|...|::|:.||       ...|:||:.::.: :::|    .:.:....:::
  Rat   113 ILKKAITLSEDEEWKRLRTLLSPTFTSGKLKEMFPIINQYADLLV-KNVK----HEAEKGNPITM 172

  Fly   184 KDRISRFTLNSICETAMGIKLDEMAEKGDRY------RANFHIIDEGLTRRIVNPLYWDDCVYNM 242
            ||....::::.|..|:.|:.:|.:....:.:      ...|:.:|......|:.|....  |:..
  Rat   173 KDIFGAYSMDVITGTSFGVNVDSLNNPQNPFVQKVKKLLKFNFLDPFFLSVILFPFLTP--VFEA 235

  Fly   243 FTGHKYNAALKVVHEFSREIIAKRRVLLEEELENRRATQTADDDICVIRKKRFAMLDTLICAEK- 306
            |.          :..|.::::...|..:|...|||...:.         |:|...|..:|.::.
  Rat   236 FD----------ITVFPKDVMKFFRTSVERMKENRMQEKV---------KQRLDFLQLMINSQSS 281

  Fly   307 ------DGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSN 365
                  .||.|...:::.:..:.| ||:|||..|.|.|..::.:...|:....|| :..|.:.:.
  Rat   282 GDKESHQGLTDVEIVAQSIFFIFA-GYETTSSALSFALYLLATHPDLQKKLQDEI-DAALPNKAP 344

  Fly   366 LNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYW 430
            :....|.::.||...:.||:||:|....:.|...::.|: ||:.:||.:.:.:..|.:|::||.|
  Rat   345 VTYDVLVEMEYLDMVLNETLRLFPVGGRLERVCKKDVEI-NGVFIPKGTVVMVPTFALHKDPKCW 408

  Fly   431 ESPEEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKS 495
            ..||||.||||..:|....:||.|:||..|.|||||.::|:..||..:|.:|::|..       .
  Rat   409 PEPEEFCPERFRKKNQDSINPYIYLPFGNGPRNCIGMRFALMNMKIALVRVLQNFSF-------G 466

  Fly   496 IVFQVGITLRFKNK 509
            :..:..|.|:.:.|
  Rat   467 LCKETQIPLKLRKK 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	CYP4	83..512	CDD:410721	103/458 (22%)
Cyp3a62	NP_001019403.1	CYP3A	67..492	CDD:410743	103/460 (22%)