Protein Alignment Cyp4p2 and CYP4A11

DIOPT Version :9

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_000769.2
• Gene: CYP4A11 / 1579
• HGNCID: 2642
• Length: 519
• Species: Homo sapiens
• Alignment Length: 409
• Identity: 122/409 - (29%)
• Similarity: 217/409 - (53%)
• Gaps: 32/409 - (7%)

  Fly   120 YNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLKFV----SQFQGQNEVV 180
            |.||.|::..|:|....:.|...|.|||..||.|||..:..: :|:|::.:    .:..||:. .
Human   120 YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL-MADSVRVMLDKWEELLGQDS-P 182

  Fly   181 VSLKDRISRFTLNSICETAM----GIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDCVYN 241
            :.:...:|..||::|.:.|.    .|::|..::.   |......::..:..|:.|..:.:|.:|:
Human   183 LEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQS---YIQAISDLNNLVFSRVRNAFHQNDTIYS 244

  Fly   242 MFTGHKY-NAALKVVHEFSREIIAKRRVLLEEELENRRATQTADDDICVIRKKRFAMLDTLICA- 304
            :.:..:: :.|.::.|:.:.::|..|:..|::|.|..:          :.||:....||.|:.|
Human   245 LTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEK----------IKRKRHLDFLDILLLAK 299

  Fly   305 -EKDGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSNLNL 368
             |...::.|..:..||||.|.||:|||:.|:.:.|..::.:...||.|.:||.. :|.|.:::..
Human   300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHS-LLGDGASITW 363

  Fly   369 SQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYWESP 433
            :.|.::.|....|||.:||||.:|.:||:........:|..|||...:.:.::.:|.|||.|.:|
Human   364 NHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 428

  Fly   434 EEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVF 498
            |.|.|.||.|.:.  :|.:|::|||.|.|||||:::||.|:|....:.|..|::||  ||..|..
Human   429 EVFDPFRFAPGSA--QHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLP--DPTRIPI 489

  Fly   499 QVG-ITLRFKNKIKVKLVR 516
            .:. :.|:.||.|.::|.|
Human   490 PIARLVLKSKNGIHLRLRR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	120/405 (30%)
CYP4A11	NP_000769.2	p450	52..505	CDD:278495	120/404 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154856
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850