Protein Alignment Cyp4p2 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_569092.2
• Gene: Cyp26a1 / 154985
• RGDID: 620161
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 458
• Identity: 100/458 - (21%)
• Similarity: 173/458 - (37%)
• Gaps: 82/458 - (17%)

  Fly    61 FDLLGKDTDQVFTH---LRQLAKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITKGVIYNF 122
            |...|:....|...   |:...:..|..|..:..|.....|:.|.|...||...:.:........
  Rat    51 FPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPAS 115

  Fly   123 LHPFLRTGVLTATEKKWH-TRRSMLTRTFHLDILNQFQEIFIAESLKFVSQFQGQNEVVVSLKDR 186
            :...|..|.|:......| .|:.::.:.|:.:.|..:..:...|....:.|:....|..:.:...
  Rat   116 VRTILGAGCLSNLHDSSHKQRKKVIMQAFNREALQCYVPVIAEEVSGCLEQWLSCGERGLLVYPE 180

  Fly   187 ISRFTLNSICETAMGIKLDEMAEKGDRYRANFHIID--EGLTRRIVN-PLYWDDCVYNMFTGHKY 248
            :.|..........:|.:........|..:    :::  |.:||.:.: |:  |.....::.|.|
  Rat   181 VKRLMFRIAMRILLGCEPGPAGGGEDEQQ----LVEAFEEMTRNLFSLPI--DVPFSGLYRGVK- 238

  Fly   249 NAALKVVHEFSREIIAKRRVLLEEELENR-RATQTADDDI-CVIRKKRFAMLDTLICAEKDGLID 311
                      :|.:|..|   :||.:..: |..|.|:.|. |                 ||.|..
  Rat   239 ----------ARNLIHAR---IEENIRAKIRRLQAAEPDAGC-----------------KDALQL 273

  Fly   312 DIGIS-EEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDL------------ 363
            .|..| |..:.|..:....:|..|:||....:..||...:.|..:..|:|..:
  Rat   274 LIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCK 338

  Fly   364 ----SNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIH 424
                ..|::..|.:|.|:|..||||:||.|.:|...|..|:..|| ||..:||...:...:.|.|
  Rat   339 SHHEDKLDMETLEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQIPKGWNVIYSICDTH 402

  Fly   425 RNPKYWESPEEFRPERFLPQNCLKRHP-----YAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKH 484
            .....:.:.|||.|:||     ...||     :::|||..|.|:|:|:::|.        ::||.
  Rat   403 DVADSFTNKEEFNPDRF-----TSLHPEDTSRFSFIPFGGGLRSCVGKEFAK--------ILLKI 454

  Fly   485 FKI 487
            |.:
  Rat   455 FTV 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	CYP4	83..512	CDD:410721	96/433 (22%)
Cyp26a1	NP_569092.2	cytochrome_P450	55..490	CDD:477761	99/454 (22%)