Protein Alignment Cyp4p2 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 540
• Identity: 158/540 - (29%)
• Similarity: 255/540 - (47%)
• Gaps: 83/540 - (15%)

  Fly     6 LWISVAILVVIHWIYKVNKDYNILAFFARRVQTKDGKPLDSLVPMIKGRTVFANCFDLLGKDTDQ 70
            ||.||.||:|.  :.|      :|:...||  .|..:.|||..                |.....
Mouse    15 LWASVVILMVT--VLK------LLSLLFRR--QKLARALDSFP----------------GPPKHW 53

  Fly    71 VFTHLRQLAKNSG-DSYLQYS----------MG----FSNFNVIDAHNAANILNHPNLITKGVIY 120
            :|.|..::.|..| |..:.::          :|    |.|....|...|......|.   ...:|
Mouse    54 LFGHALEIQKTGGLDKVVTWTEQFPYAHPLWLGQFIVFLNIYEPDYAKAVYSRGDPK---AAYVY 115

  Fly   121 NFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLKFV----SQFQGQNEVVV 181
            :|...::..|:|.....||...|.:||..||.|:|..:..|| |||.:.:    .:...:|:...
Mouse   116 DFFLQWIGKGLLVLEGPKWFQHRKLLTPGFHYDVLKPYVAIF-AESTRVMLDKWEKKASENKSFD 179

  Fly   182 SLKDRISRFTLNSICETAMGIKLDEMAEKGDRYRA----NFHIIDEGLT----RRIVNPLYWDDC 238
            ...| :....|:::.:...|        |||...:    ::::....||    :||.:..|.:|.
Mouse   180 IFCD-VGHMALDTLMKCTFG--------KGDSGLSHSDNSYYLAVSDLTLLMQQRIDSFQYHNDF 235

  Fly   239 VYNMFT-GHKYNAALKVVHEFSREIIAKRRVLLEEELENRRATQTADDDICVIRKKRFAMLDTLI 302
            :|.:.. |.::..|.::.|:.:..:|.:|:..|::|.|.::..:          ::....||.|:
Mouse   236 IYWLTPHGRRFLRACQIAHDHTDHVIRQRKAALQDEKEQKKLQE----------RRHLDFLDILL 290

  Fly   303 CA-EKDGL-IDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSN 365
            .| ::.|: :.|..:..||||.|.||:|||:.|:.:.|..|:||...|:.|.:|::| ||.|..:
Mouse   291 GARDESGIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMHQQRCREEVRE-ILGDRDS 354

  Fly   366 LNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYW 430
            .....|:::.||...:||..||||.:|.:.||..:.....:|..||..|.|::|::.:|||...|
Mouse   355 FQWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVW 419

  Fly   431 ESPEEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKS 495
            ..||.|.|.||.|:|...|||:|::|||||.||||||::||.|||.:..:.|..|:..|  ||..
Mouse   420 PDPEVFDPLRFSPENMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSP--DPSK 482

  Fly   496 IVFQV-GITLRFKNKIKVKL 514
            |..:| .:.||.||.|.:.|
Mouse   483 IPIKVPQLILRSKNGIHLYL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	CYP4	83..512	CDD:410721	138/459 (30%)
Cyp4b1	NP_031849.1	CYP4B-like	67..501	CDD:410771	137/459 (30%)