Protein Alignment Cyp4p2 and Cyp3a16

DIOPT Version :10

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 566
• Identity: 119/566 - (21%)
• Similarity: 237/566 - (41%)
• Gaps: 131/566 - (23%)

  Fly     8 ISVAILVVI--------HWIYKVNKDYNILAFFARRVQTKDGKPLDSLVPMIKGRTVFANCFDLL 64
            :.:||::|:        |.::|                 |.|.|....:|.:
Mouse    13 VLLAIILVLLYRYGTCTHGLFK-----------------KQGIPGPKPLPFL------------- 47

  Fly    65 GKDTDQVFTHLRQLAKNSGDSYLQYSMGFSNFNVIDAHNAANILNHP----NLITKGV--IYNFL 123
                ..|..:.:.|.|...:.|.:|.   ..:.:.|......::..|    |::.|..  ::...
Mouse    48 ----GTVLNYYKGLWKFDMECYEKYG---KTWGLFDGQIPLFVITDPETIKNVLVKECFSVFTNR 105

  Fly   124 HPFLRTGVLT-----ATEKKWHTRRSMLTRTF-------HLDILNQFQEIFIAESLKFVSQFQGQ 176
            ..|...|:::     |.:::|...|::|:.||       ...::.|:.:|.:    |::.| :.:
Mouse   106 QDFFPVGIMSKSISLAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILV----KYLRQ-EAE 165

  Fly   177 NEVVVSLKDRISRFTLNSICETAMGIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDC--- 238
            ....|::||.:..::::.|..|..|:.:|.:....|.:..|        .::::...|:|..
Mouse   166 KGKPVAVKDVLGAYSMDVIISTTFGVNIDSLNNPEDPFVEN--------AKKVLRFDYFDPLSLS 222

  Fly   239 ---------VYNMFTGHKYNAALKVVHEFSREIIAKRRVLLEEELENRRATQTADDDICVIRKKR 294
                     :|.|..          :..|.::.|...:..::...|||..::         :|.|
Mouse   223 VALFPFLTPIYEMLN----------ICMFPKDSIEFFKKFVDRMTENRLDSK---------QKHR 268

  Fly   295 FAMLDTLICA-----EKDG--LIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCY 352
            ...:..::.|     :||.  .:.:|.|:.:....:..||:|||..|.|.:.:::.:...|:...
Mouse   269 VDFIYLMMEAYNKSKDKDSHKALSEIEITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQ 333

  Fly   353 QEIQEHILDDLSNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQIN 417
            :||.| .|.:.:......:..:.||...:.||:||||....:.|...::.|: ||:.:||.|.:.
Mouse   334 EEIDE-ALPNKAPPTYDTVMAMEYLDMVLNETLRLYPITNRLQRVCKKDVEI-NGIYIPKGSTVI 396

  Fly   418 IHVFDIHRNPKYWESPEEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVIL 482
            |..:.:|.:|::|..||||:||||..:|.....||.|:||..|.|||||.::|:..||..::.:|
Mouse   397 IPSYVLHHDPQHWPEPEEFQPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVL 461

  Fly   483 KHFKILPVIDPKSIVFQVGITLRFKNK--------IKVKLVRRNCV 520
            ::|...|..:.:       |.|:...:        |.:|:|.|:.|
Mouse   462 QNFSFQPCKETQ-------IPLKLSRELLLQPVKPIVLKVVPRDAV 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	CYP4	83..512	CDD:410721	103/473 (22%)
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	102/469 (22%)