DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and LHX4

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_203129.1	Gene:	LHX4 / 89884	HGNCID:	21734	Length:	390	Species:	Homo sapiens

Alignment Length:	101	Identity:	28/101 - (27%)
Similarity:	44/101 - (43%)	Gaps:	14/101 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 CSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQI 352
            |.:|.....:::....|.|              |.||..|::||..|:..:......:...|.|:
Human   140 CKEDYETAKQNDDSEAGAK--------------RPRTTITAKQLETLKNAYKNSPKPARHVREQL 190

  Fly   353 ATSLKLSEVQVKIWFQNRRAKWKRVKAGLTSHGLGR 388
            ::...|....|::||||||||.||:|.....|..|:
Human   191 SSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQ 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	17/50 (34%)
LHX4	NP_203129.1	LIM1_Lhx4	30..81	CDD:188852
		LIM2_Lhx3_Lhx4	89..144	CDD:188762	1/3 (33%)
		Homeobox	160..213	CDD:306543	18/52 (35%)
		Interaction with DNA. /evidence=ECO:0000305\|PubMed:28473536	161..181		6/19 (32%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000305\|PubMed:28473536	199..211		7/11 (64%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	230..253
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	356..390
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910