DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and LBX2

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001269359.1	Gene:	LBX2 / 85474	HGNCID:	15525	Length:	198	Species:	Homo sapiens

Alignment Length:	160	Identity:	55/160 - (34%)
Similarity:	70/160 - (43%)	Gaps:	41/160 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 AQSRHEGGGMGGKDSQGNGSSSNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKL 358
            |::.....|..|.|:.|.|.... |.|:.|||||::|:|||||.|..:|||:.:||..:||.|.|
Human    61 ARALQPSEGRAGPDALGPGPFGR-KRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGL 124

  Fly   359 SEVQVKIWFQNRRAKWKR----VKAG-----------LTSHGLGRNGTTSGTKIVVPIPVHVNRF 408
            :..||..||||||||.||    ::|.           |.|..|.......|
Human   125 ANAQVVTWFQNRRAKLKRDVEEMRADVASLRALSPEVLCSLALPEGAPDPG-------------- 175

  Fly   409 AVRSQHQQLEKMCLSGPKPDLRKKLSAEAI 438
                       :||....||.|..||.|.|
Human   176 -----------LCLGPAGPDSRPHLSDEEI 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	30/50 (60%)
LBX2	NP_001269359.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	24..46
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..89		7/26 (27%)
		Homeobox	88..141	CDD:278475	31/52 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..198		10/47 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910