DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and LHX3

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_055379.1	Gene:	LHX3 / 8022	HGNCID:	6595	Length:	402	Species:	Homo sapiens

Alignment Length:	184	Identity:	45/184 - (24%)
Similarity:	75/184 - (40%)	Gaps:	49/184 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 HSSPAK-SGSHSPM-EPALDVG-----MDEDFECSGDSCSDISLTMSPRNYNGEMDKSRNGAY-- 280
            ||...| |..|:|: |.....|     .|:.|:..|..|:...|.:.|...   :.::::..|
Human    57 HSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQV---VRRAQDFVYHL 118

  Fly   281 -------------TNSD---SED----C-SDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRRRRT 324
                         |..:   .||    | :|.|.|:.|                .:.:.::|.||
Human   119 HCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQR----------------EAEATAKRPRT 167

  Fly   325 AFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVK 378
            ..|::||..|:..::.....:...|.|:::...|....|::||||||||.||:|
Human   168 TITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLK 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	17/50 (34%)
LHX3	NP_055379.1	LIM1_Lhx3b	33..87	CDD:188851	9/29 (31%)
		LIM2_Lhx3_Lhx4	95..150	CDD:188762	8/57 (14%)
		Homeobox	165..218	CDD:278475	18/52 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910