Protein Alignment unpg and NKX2-1

DIOPT Version :9

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001073136.1
• Gene: NKX2-1 / 7080
• HGNCID: 11825
• Length: 401
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 106/440 - (24%)
• Similarity: 149/440 - (33%)
• Gaps: 152/440 - (34%)

  Fly    66 LSARAMVASSALGLTQF---PLYNPWLHGYFAQNHERLTHLIAGGCYLPSSPAGHPAAQQPQAQA 127
            ||.|.:::.|....|.|   .:.:|....|      :...:..||       .|.|.|...|.||
Human    25 LSRRRIMSMSPKHTTPFSVSDILSPLEESY------KKVGMEGGG-------LGAPLAAYRQGQA 76

  Fly   128 QPQPPPPHPPTHALEKQLPPTLPHPLDTR---FLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSL 189
            .       |||.|:::       |.:...   ...::..||||
Human    77 A-------PPTAAMQQ-------HAVGHHGAVTAAYHMTAAGV---------------------- 105

  Fly   190 SVHARLQHMAAAGRMHEDQANPGMAQLQEPTPPQAHSSPAKSGSH-SPMEPALDVGMDEDFECSG 253
               .:|.|.|..|..:.:..|.......:.|...:.|.|...|:: .|..||
Human   106 ---PQLSHSAVGGYCNGNLGNMSELPPYQDTMRNSASGPGWYGANPDPRFPA------------- 154

  Fly   254 DSCSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSS--- 315
                 ||..|.|.:   .|:.|                          ||||..|.|:.|.:
Human   155 -----ISRFMGPAS---GMNMS--------------------------GMGGLGSLGDVSKNMAP 185

  Fly   316 --NSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRV- 377
              ::..|:||..|:..|:.||||.|..:||||..||..:|:.:.|:..||||||||.|.|.||.
Human   186 LPSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQA 250

  Fly   378 --KAG-----LTSHGLGRNGTT-----------SGTKIVVPIPVHVNRFAVRSQHQQLEKMCLSG 424
              ||.     ..|.|.|..|.|           |..::.||:.|...            |.|.:|
Human   251 KDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDG------------KPCQAG 303

  Fly   425 -PKPDLRKKLSAEAIGGFEKFSGSTNASSPSGGPVGLGVGVGVGVGVGLG 473
             |.|      .|.::.|..:......|.:.......:.||.|   |.|||
Human   304 APAP------GAASLQGHAQQQAQHQAQAAQAAAAAISVGSG---GAGLG 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	25/50 (50%)
NKX2-1	NP_001073136.1	Homeobox	194..247	CDD:278475	27/52 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910