DRSC/TRiP Functional Genomics Resources

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Protein Alignment unpg and lbx2

DIOPT Version :9

Sequence 1:NP_477146.1 Gene:unpg / 35942 FlyBaseID:FBgn0015561 Length:485 Species:Drosophila melanogaster
Sequence 2:NP_001007135.1 Gene:lbx2 / 64276 ZFINID:ZDB-GENE-001206-2 Length:257 Species:Danio rerio


Alignment Length:254 Identity:73/254 - (28%)
Similarity:96/254 - (37%) Gaps:79/254 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   228 PAKSGSHSPMEPALDVGMDEDFECSGDSCSDISLTMSPRNYNGEM------------DKSRNGAY 280
            |..:.|:.|:.|.              |..||....|.:...|.:            ..||||..
Zfish    30 PPPANSNKPLTPF--------------SIEDILNKPSVKKSVGSLCPPRVLEKVTGSSASRNGIS 80

  Fly   281 TNSDSEDCSDDEGAQSRHEG-------GGMGGKDSQGNGSSSNSKSRRR-RTAFTSEQLLELERE 337
            ..| |..|:.:|.|....:|       ...|.:.....|....||.||: |||||:.|:.|||:.
Zfish    81 APS-SPLCALEELASKTFKGLEVSVIQAAEGREHINAFGQRQASKKRRKSRTAFTNHQIYELEKR 144

  Fly   338 FHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR----VKAGLTSHGLGRNGTTSGTKIV 398
            |..:||||..:|.|||..|.|:..||..||||||||.||    :||.:.|               
Zfish   145 FLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVES--------------- 194

  Fly   399 VPIPVHVNRFAVRSQHQQLEKMCLSGPKPDLRKKLSAEAIGGFEKFSGSTNASSPSGGP 457
                              |:|:    |...|:|.:|.|   ..|...|.:...|||..|
Zfish   195 ------------------LKKI----PPQALQKLVSME---DMEDAHGGSGPISPSLSP 228

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
unpgNP_477146.1 Homeobox 324..375 CDD:278475 29/50 (58%)
lbx2NP_001007135.1 Required for convergent extension movement and hypaxial myogenesis during gastrulation. Required for the formation of thick and thin myofilaments. Required for myod1 expression in the pectoral fin bud. Required for continuous expression of cxcl12a in the posterior lateral mesoderm at the tail bud stage and in adaxial cells at the 10-somite stage. /evidence=ECO:0000269|PubMed:19216761, ECO:0000269|PubMed:22216300, ECO:0000269|PubMed:22406073 1..46 5/29 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..43 4/26 (15%)
Homeobox 129..183 CDD:395001 30/53 (57%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 206..257 8/26 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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