DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and hoxb10a

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_571616.1	Gene:	hoxb10a / 58056	ZFINID:	ZDB-GENE-000328-2	Length:	279	Species:	Danio rerio

Alignment Length:	294	Identity:	80/294 - (27%)
Similarity:	122/294 - (41%)	Gaps:	54/294 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 HPPTHAL-----EKQLPPTLPH----PL-------DTRFLPFNPAAAGVAPTDLS-YRRLAELMN 182
            ||..|..     |:..|..|||    |.       |..:...:|......|.|:| :.|:  :.:
Zfish     6 HPFVHGAASWDGEQPSPVQLPHISACPFTSSGRKEDPFYFTLDPTGQARQPLDISAFSRI--MTD 68

  Fly   183 QDYVHSLSVHARLQHMAAAGRMHEDQANPGMAQLQEPTPPQAHSSPAKSGSHSPMEPALDVGMDE 247
            ...::|...| |.:....:|  |:      :..|...|.|:   ||:.| |||..:....:.:..
Zfish    69 MGSLNSADDH-RPETSFYSG--HK------LLSLNTNTDPE---SPSLS-SHSDSQHLHSLSLSA 120

  Fly   248 DFECS-GDSCSDIS-LTMSPRNYNGEMDKSRNG---AYTNSDSEDCSDDEGAQSRHEGGGMGGK- 306
              .|| .|:..|:. |.|....|..:..:||..   ..|.|.|:...||....:.......|.|
Zfish   121 --PCSETDNKHDMQYLAMESTKYPSQWSESRTNRSIITTLSISQRSKDDIEPNNLQTDFTRGDKT 183

  Fly   307 ----------DSQGNGSSSNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEV 361
                      ::..||..|....|::|..::..|:||||:||....||:...|.:|:.|:.|::.
Zfish   184 PREKTQDVTLENAANGWLSAKAGRKKRCPYSKHQILELEKEFLFNMYLTRERRLEISRSINLTDR 248

  Fly   362 QVKIWFQNRRAKWKRVKAGLTSHGLGRNGTTSGT 395
            ||||||||||.|.|:    :|.....|:..||.|
Zfish   249 QVKIWFQNRRMKLKK----MTREHRTRDPGTSFT 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	24/50 (48%)
hoxb10a	NP_571616.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	91..112		9/24 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	167..187		3/19 (16%)
		Homeobox	209..262	CDD:278475	25/52 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910