DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and hoxa1a

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_571611.1	Gene:	hoxa1a / 58051	ZFINID:	ZDB-GENE-000823-5	Length:	329	Species:	Danio rerio

Alignment Length:	307	Identity:	82/307 - (26%)
Similarity:	105/307 - (34%)	Gaps:	111/307 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 AQQPQAQAQPQPPPPHPPTHALEKQLPPTL-----PHPLDTRFLPFNPAAAGVAPTDLSYRRLAE 179
            :.|....:|||        .|...|.|.||     .||           :.|.......|...|
Zfish    58 SSQDVINSQPQ--------QAGSYQSPGTLSITYSAHP-----------SYGTQSFCTGYNHYA- 102

  Fly   180 LMNQDYVHSLSV------------------HARLQHMAAAGRMH---------------EDQAN- 210
             :|||...|:|.                  |...:|..::|.:|               .||||
Zfish   103 -LNQDVESSVSFPQCGPLVYSGNISSTVVQHRHHRHGYSSGNVHLHGQFQYGSATYGNSSDQANL 166

  Fly   211 PGMAQLQEPTPPQAHSSPAKSGSHSPMEPALDVGMDEDFECSGDSCSDISLTMSPRNYNGEMDKS 275
            ..:|....|..| .| .|......||:...:..|...|:                      |...
Zfish   167 TFVAGCSNPLSP-LH-VPHHDACCSPLSDGVPTGQTFDW----------------------MKVK 207

  Fly   276 RNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRRRRTAFTSEQLLELEREFHA 340
            ||...|....|              .|.||:.:            ..||.|:::||.|||:|||.
Zfish   208 RNPPKTGKAGE--------------YGFGGQPN------------TVRTNFSTKQLTELEKEFHF 246

  Fly   341 KKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKW-KRVKAGLTSHGL 386
            .|||:...|.:||.||:|:|.||||||||||.|. ||.|.||....|
Zfish   247 NKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPKSL 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	31/51 (61%)
hoxa1a	NP_571611.1	Antp-type hexapeptide	200..205		1/26 (4%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..227		7/44 (16%)
		Homeobox	229..281	CDD:278475	32/51 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	277..329		8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910