Protein Alignment unpg and BARHL1

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_064448.1
• Gene: BARHL1 / 56751
• HGNCID: 953
• Length: 327
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 83/284 - (29%)
• Similarity: 118/284 - (41%)
• Gaps: 65/284 - (22%)

  Fly   209 ANPGMAQLQEPTP-PQAHSSPAKSGSHSPME---PALDVGMDEDF-------ECSG-DSCSDISL 261
            |:||...|:..|| |...|.|.......|.:   ||....:...|       :|.. .:|:..|.
Human    52 ASPGRDCLETGTPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSS 116

  Fly   262 TMSP--------------RNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNG 312
            :..|              .::..::|||  |:..:||||....:||             |.:.:.
Human   117 SGQPAAPEPGGRLAAKAAEDFRDKLDKS--GSNASSDSEYKVKEEG-------------DREISS 166

  Fly   313 SSSN-----SKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRA 372
            |..:     .|.|:.|||||..||.:|||.|..:||||:.:|.::|.||.|::.|||.|:||||.
Human   167 SRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRT 231

  Fly   373 KWKRVKA-GLTSHGLGRNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEKMCL-------SGPKPDL 429
            ||||..| ||..  |...|..|..:.:.|.|.    |..:|....|:....       |.|.|.|
Human   232 KWKRQTAVGLEL--LAEAGNYSALQRMFPSPY----FYPQSLVSNLDPGAALYLYRGPSAPPPAL 290

  Fly   430 RKKLSAEAIGGFEKFSGSTNASSP 453
            ::.|....:     ..|...||.|
Human   291 QRPLVPRIL-----IHGLQGASEP 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	29/51 (57%)
BARHL1	NP_064448.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..90		12/37 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..184		17/86 (20%)
		Homeodomain	179..235	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..327		3/5 (60%)