DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment unpg and MEOX2

DIOPT Version :9

Sequence 1:NP_477146.1 Gene:unpg / 35942 FlyBaseID:FBgn0015561 Length:485 Species:Drosophila melanogaster
Sequence 2:NP_005915.2 Gene:MEOX2 / 4223 HGNCID:7014 Length:304 Species:Homo sapiens


Alignment Length:286 Identity:82/286 - (28%)
Similarity:107/286 - (37%) Gaps:92/286 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   149 LPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQHMA------------AA 201
            :.|||.......:..|.|:.|...|              ||::|.|..||:            .|
Human     1 MEHPLFGCLRSPHATAQGLHPFSQS--------------SLALHGRSDHMSYPELSTSSSSCIIA 51

  Fly   202 GRMHED-------------------------------QANPGMAQLQEPTPPQAHSSPAKSGSHS 235
            |..:|:                               |.|..:.|:..|.....||...:..|..
Human    52 GYPNEEGMFASQHHRGHHHHHHHHHHHHHQQQQHQALQTNWHLPQMSSPPSAARHSLCLQPDSGG 116

  Fly   236 PMEPALDVGMDEDFECSGD----SCSDISLTMSPRNYN------GEMDKSRNGAYTNSDSEDCSD 290
            |.|    :|......||..    |.:......:|.:|.      .|.:| |:|....|||.|   
Human   117 PPE----LGSSPPVLCSNSSSLGSSTPTGAACAPGDYGRQALSPAEAEK-RSGGKRKSDSSD--- 173

  Fly   291 DEGAQSRHEGGGMGGKDSQGNGSSS-NSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIAT 354
                            ..:||..|. |||.|:.|||||.||:.|||.||....||:...|.:||.
Human   174 ----------------SQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAV 222

  Fly   355 SLKLSEVQVKIWFQNRRAKWKRVKAG 380
            :|.|:|.|||:||||||.||||||.|
Human   223 NLDLTERQVKVWFQNRRMKWKRVKGG 248

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
unpgNP_477146.1 Homeobox 324..375 CDD:278475 29/50 (58%)
MEOX2NP_005915.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 63..192 30/152 (20%)
COG5576 160..284 CDD:227863 50/109 (46%)
Homeobox 191..243 CDD:278475 30/51 (59%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X14
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.