DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and pitx3

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_991238.1	Gene:	pitx3 / 402974	ZFINID:	ZDB-GENE-041229-4	Length:	293	Species:	Danio rerio

Alignment Length:	201	Identity:	60/201 - (29%)
Similarity:	93/201 - (46%)	Gaps:	39/201 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   274 KSRNGAYTNSDS-----------EDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRRRRTAFT 327
            ::|:.|.:.|||           :|.||.|.:...|.      .:|.....|...|.||:||.||
Zfish    10 EARSPALSLSDSGTPQHDPGCKGQDNSDTEKSHQNHT------DESNPEDGSLKKKQRRQRTHFT 68

  Fly   328 SEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR----VKAGLTSHGLGR 388
            |:||.|||..|...:|..::.|.:||....|:|.:|::||:||||||::    .:|.|..:|.|.
Zfish    69 SQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGA 133

  Fly   389 --NGTTSGTKIVVPIPVHVNRFAVRSQHQQLEKMCLSGPKPDLRKKLSAEAIGGFEKFSGSTNAS 451
              ||      ::.|   :.:.::..|.:....|...|.|       |||::...|...:.|..:|
Zfish   134 QFNG------LMQP---YDDMYSGYSYNNWATKSLASSP-------LSAKSFPFFNSMNVSPLSS 182

  Fly   452 SPSGGP 457
            .|...|
Zfish   183 QPMFSP 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	24/50 (48%)
pitx3	NP_991238.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..69		18/64 (28%)
		Cnd2	18..>79	CDD:303063	23/66 (35%)
		Homeobox	64..116	CDD:278475	25/51 (49%)
		OAR	251..268	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	255..268
		Nuclear localization signal. /evidence=ECO:0000250\|UniProtKB:O35160	260..264
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910