DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and UNCX

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001073930.1	Gene:	UNCX / 340260	HGNCID:	33194	Length:	531	Species:	Homo sapiens

Alignment Length:	357	Identity:	93/357 - (26%)
Similarity:	120/357 - (33%)	Gaps:	119/357 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 LPHPLDTRFLPFNPAAAGVA--PTDLSYRRLAELMNQDYVHSLSVHARLQHMAAA--------GR 203
            |.||    ...|..:..||.  |..|.:.         :|:.|:.| :||..|||        |.
Human     7 LEHP----HAQFGGSLGGVVGFPYPLGHH---------HVYELAGH-QLQSAAAAASVPFSIDGL 57

  Fly   204 MHEDQANPGMAQLQEPTPPQAHSSPAKSGSHSPMEPALDVGMD-EDFECSGDSCSDISLTMSPRN 267
            :....|  ..|.:..|||    ..||..|          ||.| :.|:.| ||
Human    58 LGGSCA--AAASVVNPTP----LLPAACG----------VGGDGQPFKLS-DS------------ 93

  Fly   268 YNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRRRRTAFTSEQLL 332
              |:.||         :|..|                             |.||.||.||..||.
Human    94 --GDPDK---------ESPGC-----------------------------KRRRTRTNFTGWQLE 118

  Fly   333 ELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKAGLTSHGLGRNGTTSGTKI 397
            |||:.|:...|..:..|..:|..|.|.|.:|::|||||||||:  |...|..|.||....|....
Human   119 ELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWR--KKENTKKGPGRPAHNSHPTT 181

  Fly   398 VVPIPVHVNRFAVRSQHQQLEKMCLSGPKPDLRKKL------SAEAIGGFEKFSGSTNASSPSGG 456
            ....|:.....|    .::||||  ...|....|||      ...:.||....|..::.|...||
Human   182 CSGEPMDPEEIA----RKELEKM--EKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGG 240

  Fly   457 -----------PVGLGVGVGVGVGVGLGVSTP 477
                       |...|.|.......|...:.|
Human   241 GLSPEPPEPPPPAAKGPGAHASGAAGTAPAPP 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	24/50 (48%)
UNCX	NP_001073930.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	87..107		10/72 (14%)
		Homeobox	108..161	CDD:306543	25/52 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..312		27/120 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..344
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	401..531
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910