DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and VSX2

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_878314.1	Gene:	VSX2 / 338917	HGNCID:	1975	Length:	361	Species:	Homo sapiens

Alignment Length:	253	Identity:	66/253 - (26%)
Similarity:	98/253 - (38%)	Gaps:	70/253 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 PPQAHSSPAKSG--------SHSPMEPA----------------------LDVGMDEDFECSGDS 255
            ||.:|...|..|        :.|.:.||                      |:|..|..
Human    44 PPSSHPRAALDGLAPGHLLAARSVLSPAGVGGMGLLGPGGLPGFYTQPTFLEVLSDPQ------- 101

  Fly   256 CSDISLTMSP-RNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKS 319
                |:.:.| ...:|.:|.|:.   .:|||||.|..:...|:           .....:...|.
Human   102 ----SVHLQPLGRASGPLDTSQT---ASSDSEDVSSSDRKMSK-----------SALNQTKKRKK 148

  Fly   320 RRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKW-KRVKAGLTS 383
            ||.||.|||.||.|||:.|:...|..:..|..:|...:|.|.::::||||||||| ||.|....|
Human   149 RRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRS 213

  Fly   384 HGLGRNGTTSG-TKIVVPIPVHVNRFA-----------VRSQHQQ-LEKMCLSGPKPD 428
            ..:...|.... .:..:|:|..:.:.|           :...|:: ||....||.||:
Human   214 SVMAEYGLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPE 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	24/51 (47%)
VSX2	NP_878314.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	104..151		13/60 (22%)
		Homeobox	153..205	CDD:395001	24/51 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..300		4/10 (40%)
		OAR	300..318	CDD:397759
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	304..317
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	313..361
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910