Protein Alignment unpg and HOXD8

DIOPT Version :9

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_062458.1
• Gene: HOXD8 / 3234
• HGNCID: 5139
• Length: 290
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 74/287 - (25%)
• Similarity: 94/287 - (32%)
• Gaps: 110/287 - (38%)

  Fly   112 SSPAGHPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRR 176
            :|.||.|.| .|||.|.|.|.||                           |:..|...
Human    56 NSAAGFPHA-PPQAHAHPHPSPP---------------------------PSGTGCGG------- 85

  Fly   177 LAELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPG----MAQLQEPTPPQAHSSPAKSGSHSPM 237
             .|...|:|.|                       ||    .|..|...||..|..|       |.
Human    86 -REGRGQEYFH-----------------------PGGGSPAAAYQAAPPPPPHPPP-------PP 119

  Fly   238 EPALDVGMDEDFECSGDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDS------EDCSDDEGAQS 296
            .|.         .|.|.:|..     .|..:.|..:..|...:|....      .||
Human   120 PPP---------PCGGIACHG-----EPAKFYGYDNLQRQPIFTTQQEAELVQYPDC-------- 162

  Fly   297 RHEGGGMGGKDSQGNGSSSNSK------------SRRRRTAFTSEQLLELEREFHAKKYLSLTER 349
            :...|.:|......|.|||.|:            .||.|..::..|.||||:||....||:...|
Human   163 KSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRR 227

  Fly   350 SQIATSLKLSEVQVKIWFQNRRAKWKR 376
            .:::.:|.|:|.||||||||||.|||:
Human   228 IEVSHALALTERQVKIWFQNRRMKWKK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	24/50 (48%)
HOXD8	NP_062458.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..127		28/141 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..200		10/46 (22%)
		Homeobox	201..253	CDD:278475	25/51 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..290		74/287 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810