Protein Alignment unpg and HOXD3

DIOPT Version :9

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_008829.3
• Gene: HOXD3 / 3232
• HGNCID: 5137
• Length: 432
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 115/512 - (22%)
• Similarity: 161/512 - (31%)
• Gaps: 209/512 - (40%)

  Fly     1 MERPALLQN----GEIGTMESPTT---RLASKPFPKPFSIESLIANQTPATATPPSPPEERDQEQ 58
            |::.|..:|    |..|..::..|   ....:|:|.|.:..||..:. |.:|
Human    17 MQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDY-PGSA------------- 67

  Fly    59 EAEQEQELSARAMVASSALGLTQFPLYNPWLHGYFAQNHERLTHLIAGGCYLP---SSPAGHPAA 120
                       ..:.|||      ||..|...|  |:        :.|.|..|   :|..|...:
Human    68 -----------CSIQSSA------PLRAPAHKG--AE--------LNGSCMRPGTGNSQGGGGGS 105

  Fly   121 QQPQAQAQPQPPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDY 185
            |.|...::.|||.|.||        |||||        |.:|
Human   106 QPPGLNSEQQPPQPPPP--------PPTLP--------PSSP----------------------- 131

  Fly   186 VHSLSVHARLQHMAAAGRMHEDQANPGMAQLQEPTPPQAHSSPAKSGSHSPMEPALDVGMDEDFE 250
                                   .|||            ...|||...
Human   132 -----------------------TNPG------------GGVPAKKPK----------------- 144

  Fly   251 CSGDSCSDISLTMSPRNYNGEMDKSRNGAYTNS---DSEDCSDDEGAQSRHEGGGMGGKDSQGNG 312
             .|.:.|..|.|:|.:.:....:..:|....||   ..|.|.|.
Human   145 -GGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDK--------------------- 187

  Fly   313 SSSNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWK-- 375
            |.....|:|.|||:||.||:|||:|||..:||....|.::|..|.|:|.|:||||||||.|:|
Human   188 SPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 252

  Fly   376 -RVKAGLTSHGL----------GRNGTTSGTKIVVPIP--------------VHVNRFAVRSQHQ 415
             :.|..|.|...          |..|..:.:..:.|:|              ...|.:.:.:...
Human   253 QKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGLAAYTA 317

  Fly   416 QLEKMCLSGPK----PDLRKKLSAEAIGGF--EKFSGS--------TNASSPSGGPV 458
            .|.. ||...|    |:......|...|||  ....||        ..:.:|:.|||
Human   318 PLSS-CLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGGNFVESMAPASGPV 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	29/50 (58%)
HOXD3	NP_008829.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..62		5/18 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..197		47/257 (18%)
		Antp-type hexapeptide	160..165		0/4 (0%)
		Homeobox	198..250	CDD:306543	30/51 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	253..280		5/26 (19%)
		DUF4074	369..430	CDD:315871	3/5 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	400..432

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810