Protein Alignment unpg and HOXC11

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_055027.1
• Gene: HOXC11 / 3227
• HGNCID: 5123
• Length: 304
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 73/313 - (23%)
• Similarity: 118/313 - (37%)
• Gaps: 89/313 - (28%)

  Fly   106 GGC----YLPSSPAGHP-----AAQQPQAQAQPQPPPPHPPTHALEKQLPPTLPHPLDTRFLPFN 161
            |.|    ||||.....|     ::..|||       |....::....|:||.            .
Human    26 GSCASNLYLPSCTYYMPEFSTVSSFLPQA-------PSRQISYPYSAQVPPV------------R 71

  Fly   162 PAAAGVAPT---------DLSYRRLAELMNQDYVHSLSV-HARLQHMAAAGRMHEDQANPGMAQL 216
            ..:.|:.|:         ...|....|||:::.:...:| ...:::..:.|..|
Human    72 EVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEGSYGGHH----------- 125

  Fly   217 QEPTPPQAHSSPA----KSGSHSPMEPALDVGMDEDFECSGDSCSDISLTMSPRNYNGEMDKSRN 277
             .|:.|  |::||    ....:|.:..|.|...|..:...||..::     .|.:..||.
Human   126 -HPSAP--HATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAE-----PPCSGKGEA----- 177

  Fly   278 GAYTNSDSEDCSDDEGAQSRHEGGGMG-GKDSQGNGSSSNS-----------------KSRRRRT 324
                 ....:.....|..||.|.|... .::...|.|||.|                 ::|::|.
Human   178 -----KGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAPNAPRTRKKRC 237

  Fly   325 AFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRV 377
            .::..|:.||||||....|::..:|.|::..|.|::.||||||||||.|.|::
Human   238 PYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKL 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	23/51 (45%)
HOXC11	NP_055027.1	DUF3528	42..161	CDD:432284	26/151 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..237		14/85 (16%)
		Homeodomain	233..289	CDD:459649	25/55 (45%)