DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and HOXC8

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_073149.1	Gene:	HOXC8 / 3224	HGNCID:	5129	Length:	242	Species:	Homo sapiens

Alignment Length:	174	Identity:	47/174 - (27%)
Similarity:	68/174 - (39%)	Gaps:	51/174 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 HSSPAKSGSHSPMEPALDVGMDEDFECSGDSCSDISLTMSPRN--YNGEMDKS-------RNGAY 280
            |.:...|.|.....|.       ...|.||:.........||.  |..:.:.|       ::.|.
Human    62 HGTSGISNSGYQQNPC-------SLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSAN 119

  Fly   281 TNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKS-------------RRRRTAFTSEQLL 332
            |||                      .:.||:.:.::|.|             |..|..::..|.|
Human   120 TNS----------------------SEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTL 162

  Fly   333 ELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR 376
            |||:||....||:...|.:::.:|.|:|.||||||||||.|||:
Human   163 ELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKK 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	24/50 (48%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	114..154		9/61 (15%)
		Antp-type hexapeptide	138..143		0/4 (0%)
		Homeobox	153..205	CDD:306543	25/51 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	206..242		0/1 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810