Protein Alignment unpg and HOXA2

DIOPT Version :9

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_006726.1
• Gene: HOXA2 / 3199
• HGNCID: 5103
• Length: 376
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 93/394 - (23%)
• Similarity: 135/394 - (34%)
• Gaps: 152/394 - (38%)

  Fly   147 PTLPHPLDTRFLPFNPAA-----AGVAPTDLSYRRLAELMNQDYVHSLSVHARLQHMAAAGRMHE 206
            |:|...|.:    |.|.|     :.:..:.||:..|.....:..:.||:..:..:| .|.||
Human    16 PSLAECLTS----FPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRH-GAGGR--- 72

  Fly   207 DQANPGMAQLQEPTPPQAHSSPAKSGSHSPME----------------PALDVGMDEDFECSGDS 255
                      .:|:|..:..||..:|:..|.|                ||.......  ..:|.:
Human    73 ----------PKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATA--AATGPA 125

  Fly   256 CSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSR 320
            |                       .::.:|.:.:|..|          ||             ||
Human   126 C-----------------------LSHKESLEIADGSG----------GG-------------SR 144

  Fly   321 RRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR---VKAGLT 382
            |.|||:|:.||||||:|||..|||....|.:||..|.|:|.|||:||||||.|.||   .|....
Human   145 RLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQN 209

  Fly   383 SHG-------------------------------LGRNGTT---------------SGTKIVVPI 401
            |.|                               |.|.|.|               :|.....|:
Human   210 SEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQSFPV 274

  Fly   402 -PVHVNRFAVRS-QHQQ---------LEKMCLSGPKPDLRKKLSAEAIGGFEKFSGS-----TNA 450
             |:..|...::. |||.         :.:.|.:|...|..:.|...::..|..||..     ::|
Human   275 SPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGLNNDSPEALEVPSLQDFSVFSTDSCLQLSDA 339

  Fly   451 SSPS 454
            .|||
Human   340 VSPS 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	31/50 (62%)
HOXA2	NP_006726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..93		14/64 (22%)
		Antp-type hexapeptide	94..99		1/4 (25%)
		Homeobox	147..200	CDD:395001	32/52 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..229		5/30 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..279		3/21 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810