Protein Alignment unpg and HOXA1

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_005513.2
• Gene: HOXA1 / 3198
• HGNCID: 5099
• Length: 335
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 80/259 - (30%)
• Similarity: 102/259 - (39%)
• Gaps: 52/259 - (20%)

  Fly   134 PHPPTHALEKQLPPTLPHPL------DTRF-LPFNPAAAGVAPTDLS--YRRLAELMNQDYVHSL 189
            |.|.|:.....|..:..|..      ...| .|::|.|.. ...|:|  |.:.|..:....:.|.
Human    75 PQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALN-QEADVSGGYPQCAPAVYSGNLSSP 138

  Fly   190 SVHARLQHMAAAGRMHEDQANPGMAQLQEPTPPQAHSSPAKSGSHSPMEPALDVGMDEDFECSGD 254
            .|.....|...||      ...|..|....:..|.|.|.|.:..::.:.| |.....|
Human   139 MVQHHHHHQGYAG------GAVGSPQYIHHSYGQEHQSLALATYNNSLSP-LHASHQE------- 189

  Fly   255 SC-SDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSK 318
            :| |..|.|.||......|...||...|....             |.|.:|    |.|..
Human   190 ACRSPASETSSPAQTFDWMKVKRNPPKTGKVG-------------EYGYLG----QPNAV----- 232

  Fly   319 SRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKW-KRVKAGL 381
                ||.||::||.|||:|||..|||:...|.:||.||:|:|.||||||||||.|. ||.|.||
Human   233 ----RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	32/52 (62%)
HOXA1	NP_005513.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..80		2/4 (50%)
		Interaction with OGT. /evidence=ECO:0000250|UniProtKB:P09022	75..203		33/142 (23%)
		COG5576	176..>286	CDD:227863	51/143 (36%)
		Antp-type hexapeptide	204..209		0/4 (0%)
		Homeodomain	233..286	CDD:459649	33/52 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..335		7/12 (58%)