DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment unpg and Hoxc5

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001101586.1	Gene:	Hoxc5 / 315341	RGDID:	1307584	Length:	222	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	68/250 - (27%)
Similarity:	90/250 - (36%)	Gaps:	92/250 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 PPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPA-AAGVAPTDLSYRRLAELMNQDYVHSLSVHAR 194
            ||.|....|.::....|        |..|..|| :|..||.....|..|..:|.......:....
  Rat    51 PPAPSNSLHGVDMAANP--------RAHPDRPACSAAAAPGHALGRDEAAPLNPGMYSQKAARPA 107

  Fly   195 LQHMA-AAGRMHEDQANPGM-AQL-QEPTPPQAHSSPAKSGSHSPMEPALDVGMDEDFECSGDSC 256
            |:..| ::|.:.|:||..|. |.| |.|.|||.:....|
  Rat   108 LEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTK-------------------------- 146

  Fly   257 SDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRR 321
                |.||                                 ||..|                 :|
  Rat   147 ----LHMS---------------------------------HETDG-----------------KR 157

  Fly   322 RRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR 376
            .||::|..|.||||:|||..:||:...|.:||.:|.|:|.|:||||||||.|||:
  Rat   158 SRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKK 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	28/50 (56%)
Hoxc5	NP_001101586.1	COG5373	65..>142	CDD:227665	25/84 (30%)
Hoxc5	NP_001101586.1	Homeobox	158..212	CDD:395001	30/53 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810