Protein Alignment unpg and HLX

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_068777.1
• Gene: HLX / 3142
• HGNCID: 4978
• Length: 488
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 102/414 - (24%)
• Similarity: 146/414 - (35%)
• Gaps: 139/414 - (33%)

  Fly    71 MVASSALGLTQFPLYNPWLHGYF---AQNHERLTHLIAGGCYLPSS-PAG--------------- 116
            :..:||..||.. |.:...|..|   |::..|.|.::|     ||. |||
Human    64 LAGASAAALTAH-LGSVHPHASFQAAARSPLRPTPVVA-----PSEVPAGFPQRLSPLSAAYHHH 122

  Fly   117 HPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPT----DLSYRRL 177
            ||..||.|.|.|.|.|||.|...||:   ||.    ..||.:| ||..:|.||.    ||.:
Human   123 HPQQQQQQQQPQQQQPPPPPRAGALQ---PPA----SGTRVVP-NPHHSGSAPAPSSKDLKF--- 176

  Fly   178 AELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPGMAQ---LQEPTPPQAHSSPAKSGSH-SPME 238
                                  ...|:...:.:|.:.:   |::.|.......||  |.| |.::
Human   177 ----------------------GIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPA--GVHLSGLQ 217

  Fly   239 PALDVGMDEDFECSGDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGM 303
            |:..     .|..|.|..::.|..:||.|.|     .||               ..|.:.:....
Human   218 PSAG-----QFFASLDPINEASAILSPLNSN-----PRN---------------SVQHQFQDTFP 257

  Fly   304 GGKDSQGNGSSSNSKSRRR---RTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKI 365
            |........:...:..|:|   |..|::.|...||:.|..:||::..:|.|:|..|.|::.|||:
Human   258 GPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKV 322

  Fly   366 WFQNRRAKWKRVKAGLTSHGLGRNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEKMCLSGPKPDLR 430
            ||||||.||:..|                                 ....|.:|...:|.||.
Human   323 WFQNRRMKWRHSK---------------------------------EAQAQKDKDKEAGEKPS-- 352

  Fly   431 KKLSAEAIGGFEKFSGSTNASSPS 454
                    ||.....|..:..|||
Human   353 --------GGAPAADGEQDERSPS 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	23/51 (45%)
HLX	NP_068777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..173		24/62 (39%)
		Homeodomain	273..333	CDD:459649	26/59 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..488		13/81 (16%)