Protein Alignment unpg and MNX1

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_005506.3
• Gene: MNX1 / 3110
• HGNCID: 4979
• Length: 401
• Species: Homo sapiens
• Alignment Length: 398
• Identity: 107/398 - (26%)
• Similarity: 139/398 - (34%)
• Gaps: 150/398 - (37%)

  Fly    29 KPFSIESLIANQTPATATPPSPPEERDQEQEAEQEQELSARAMVASSALGL------------TQ 81
            |.|.|::|:|...|..|:..|.|              |:....:|::|.|.            |
Human     5 KNFRIDALLAVDPPRAASAQSAP--------------LALVTSLAAAASGTGGGGGGGGASGGT- 54

  Fly    82 FPLYNPWLHGYFAQNHERLTHLIAGGCYLPSSPAGH--PAAQQPQAQAQPQPPPPHPPTHALEKQ 144
                                   :|.|    |||..  |||...:.:|:...||.....|.
Human    55 -----------------------SGSC----SPASSEPPAAPADRLRAESPSPPRLLAAHC---- 88

  Fly   145 LPPTLPHPLDTRFL---------------------PFNPAAAGVAPTDLSYRRLAELMNQDYVHS 188
              ..||.|   .||                     |...|||..|....:...||
Human    89 --ALLPKP---GFLGAGGGGGGTGGGHGGPHHHAHPGAAAAAAAAAAAAAAGGLA---------- 138

  Fly   189 LSVH-------ARLQHMAA--AGRMHEDQANPGMAQLQEPTPPQAHSSPAKSGSHSPMEPA---- 240
            |.:|       |.|...||  ...::...|....|.|....|..::|.|...|:| |..||
Human   139 LGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAH-PAHPADPIK 202

  Fly   241 LDVGMDEDFECSGDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGG 305
            |..|..:..:....|.:.:.|...| ::|.:                      |||...|
Human   203 LGAGTFQLDQWLRASTAGMILPKMP-DFNSQ----------------------AQSNLLG----- 239

  Fly   306 KDSQGNGSSSNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNR 370
                        |.||.||||||:||||||.:|...||||..:|.::||||.|:|.|||||||||
Human   240 ------------KCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNR 292

  Fly   371 RAKWKRVK 378
            |.||||.|
Human   293 RMKWKRSK 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	35/51 (69%)
MNX1	NP_005506.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..78		12/68 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..120		0/18 (0%)
		Homeodomain	242..298	CDD:459649	38/55 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..401		1/2 (50%)