DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and pax6a

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_009296153.1	Gene:	pax6a / 30567	ZFINID:	ZDB-GENE-990415-200	Length:	459	Species:	Danio rerio

Alignment Length:	267	Identity:	65/267 - (24%)
Similarity:	106/267 - (39%)	Gaps:	74/267 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 RNYNGEMDK--SRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNS---------KS 319
            |..||:...  :|.|.|..:......:.:|.| :.:|||........||..|:.         |.
Zfish   188 RMLNGQTGTWGTRPGWYPGTSVPGQPNQDGCQ-QSDGGGENTNSISSNGEDSDETQMRLQLKRKL 251

  Fly   320 RRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVK------ 378
            :|.||:||.||:..||:||....|..:..|.::|..:.|.|.::::||.||||||:|.:
Zfish   252 QRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQR 316

  Fly   379 ---AGLTSH----------------------------GLGRNGT--TSGTKIVVPIP--VHVNRF 408
               :..:||                            .|||:.|  |:....:.|:|  ...|..
Zfish   317 RQASNSSSHIPISSSFSTSVYQPIPQPTTPVSFTSGSMLGRSDTALTNTYSALPPMPSFTMANNL 381

  Fly   409 AVR-SQHQQLEKMCLSGPK-----------PDLRKKLSAEAIGGFEKFSGSTNASSPSGGPVGLG 461
            .:: ||......|..:.|.           |.::..::::::..    ||:|     |.|.:..|
Zfish   382 PMQPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQAHMNSQSMAA----SGTT-----STGLISPG 437

  Fly   462 VGVGVGV 468
            |.|.|.|
Zfish   438 VSVPVQV 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	21/50 (42%)
pax6a	XP_009296153.1	PAX	31..169	CDD:128645
		Homeobox	255..307	CDD:306543	22/51 (43%)
		Retinal	341..>459	CDD:330657	23/113 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910