DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and lhx5

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_571293.1	Gene:	lhx5 / 30465	ZFINID:	ZDB-GENE-980526-484	Length:	399	Species:	Danio rerio

Alignment Length:	261	Identity:	63/261 - (24%)
Similarity:	99/261 - (37%)	Gaps:	88/261 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 MDED-FECSGD----------------SCSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDE 292
            :||: |.|..|                ||:|.||  ||...:...|.::     .:|:...||
Zfish   108 IDENKFVCKEDYLSASAIKEVNLNSVSSCTDRSL--SPDLPDQIQDDTK-----ETDNSTSSD-- 163

  Fly   293 GAQSRHEGGGMGGKDSQGN-GSSSNSKSRRR--RTAFTSEQLLELEREFHAKKYLSLTERSQIAT 354
                         ||:..| ....||.::||  ||...::||..|:..|.|....:...|.|:|.
Zfish   164 -------------KDTNNNENEEQNSCTKRRGPRTTIKAKQLETLKAAFVATPKPTRHIREQLAQ 215

  Fly   355 SLKLSEVQVKIWFQNRRAKWKRVKAGLTSHGLGRNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEK 419
            ...|:...:::||||||:|.:|:|. |::.|..|:....|.:.:.|:            ..:||.
Zfish   216 ETGLNMRVIQVWFQNRRSKERRMKQ-LSALGARRHAFFRGPRRMRPL------------GGRLED 267

  Fly   420 MCLSGPKPDLRKKLSAEAIGGFE---KFSG-----------------STNASSPSGGPVGLGVGV 464
            ..:.||             ||:.   ::.|                 |:.|.||:..|..|..|.
Zfish   268 PDIMGP-------------GGYSYYGEYQGDYYGPVVNYDFFPHGPPSSQAHSPAESPYLLSSGS 319

  Fly   465 G 465
            |
Zfish   320 G 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	17/50 (34%)
lhx5	NP_571293.1	LIM1_Lhx1_Lhx5	5..56	CDD:188753
		LIM2_Lhx1_Lhx5	64..119	CDD:188761	4/10 (40%)
		COG5576	126..>242	CDD:227863	38/138 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..185		17/70 (24%)
		Homeobox	183..236	CDD:278475	18/52 (35%)
		GATA-N	298..>390	CDD:283099	8/23 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	301..399		8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910