DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and Hoxb3

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001100512.1	Gene:	Hoxb3 / 303488	RGDID:	1310780	Length:	429	Species:	Rattus norvegicus

Alignment Length:	409	Identity:	106/409 - (25%)
Similarity:	147/409 - (35%)	Gaps:	142/409 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 PPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQH 197
            ||.||..|                                     |..:..||..|......|.:
  Rat    32 PPQPPFQA-------------------------------------ATHLEGDYQRSACSLQSLGN 59

  Fly   198 MAAAGRMHEDQAN---PGMAQLQEPTPPQA----------------HSSPAKSGSHSPMEPALDV 243
            .|...:..|...:   ||:|....|.||.:                ...|:|||..
  Rat    60 AAPHAKSKELNGSCMRPGLAPEPLPAPPGSPPPSAAPTSTTSNSNNGGGPSKSGPP--------- 115

  Fly   244 GMDEDFECSGDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDS----EDCSDDEGAQSRHEGGGMG 304
                  :|...|.|.::..:.|     .|.:||..:...:.|    |.|....|      |||.|
  Rat   116 ------KCGASSNSTLTKQIFP-----WMKESRQTSKLKNSSPGTAEGCGGGGG------GGGGG 163

  Fly   305 GKDSQGNGSS---------SNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSE 360
            |..|.|.||.         .::.|:|.|||:||.||:|||:|||..:||....|.::|..|.|||
  Rat   164 GSSSGGGGSGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSE 228

  Fly   361 VQVKIWFQNRRAKWKR-VKA-GLTSHGLGRN---------GTTSGTKIVV---------PIPV-- 403
            .|:||||||||.|:|: .|| ||.|...|.:         .:|:|....:         |.|.
  Rat   229 RQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYDSPSPPAF 293

  Fly   404 ---HVNRFAVRSQHQQLEKMCLS------GPKPDLRKKLSAEAIGGFEKFSGSTNASSPSGGPVG 459
               |.|.:|:.|.:|...|.|.:      .|.|:....: .:|.|      |:....:..|.||.
  Rat   294 SKGHQNAYALPSNYQPPLKGCGAPQKYPPTPAPEYESHV-LQANG------GAYGTPTMQGSPVY 351

  Fly   460 LGVGVGVGVGVGLGVSTPL 478
            :|.|         |.:.||
  Rat   352 VGGG---------GYADPL 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	30/50 (60%)
Hoxb3	NP_001100512.1	Homeobox	191..244	CDD:395001	31/52 (60%)
Hoxb3	NP_001100512.1	DUF4074	365..427	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810