DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and hoxa2b

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_571181.1	Gene:	hoxa2b / 30325	ZFINID:	ZDB-GENE-990415-98	Length:	363	Species:	Danio rerio

Alignment Length:	205	Identity:	62/205 - (30%)
Similarity:	90/205 - (43%)	Gaps:	40/205 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 ANPGMAQLQEPTPP-----QAHSSPAKSGSHS-----PME---PALDVGM----DEDFECSGDSC 256
            :.|.:|:.....||     |:.|..:.:.|||     |.|   |:|:.|.    ....:....||
Zfish    14 SQPSLAECLTSFPPVGDAFQSSSIKSSTLSHSTLIPPPFEQTIPSLNPGSHPRHSRPKQNPNGSC 78

  Fly   257 SDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSD-------DEGAQSRHEGGGMGGKDSQGNGSS 314
             .:.....|..|....:|..:.....:.:...:|       .:|:....:||
Zfish    79 -PLPAASLPPEYPWMKEKKASKKNQTTSTAATTDPGPLYFSPQGSPEISDGG------------- 129

  Fly   315 SNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR-VK 378
             :..:||.|||:|:.||||||:|||..|||....|.:||..|.|:|.|||:||||||.|.|| .:
Zfish   130 -SGATRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 193

  Fly   379 AGLTSHGLGR 388
            .....||.|:
Zfish   194 CKENHHGDGK 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	31/50 (62%)
hoxa2b	NP_571181.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..132		17/104 (16%)
		Antp-type hexapeptide	88..93		1/4 (25%)
		Homeobox	137..189	CDD:278475	32/51 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	186..218		6/18 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	245..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900