Protein Alignment unpg and GBX2

DIOPT Version :9

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001476.2
• Gene: GBX2 / 2637
• HGNCID: 4186
• Length: 348
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 147/437 - (33%)
• Similarity: 182/437 - (41%)
• Gaps: 133/437 - (30%)

  Fly    18 PTTRLASKPF--PKPFSIESLIANQTPATATPPSPPEERDQEQEAEQEQELSARAMVASSALGLT 80
            |:..:..:|.  ...|||:|||       .:||.|                      :......|
Human     7 PSLMMMQRPLGSSTAFSIDSLI-------GSPPQP----------------------SPGHFVYT 42

  Fly    81 QFPLYNPWLHGYFAQNHERLTHLIAGGCYLPSSPAGHPAAQQPQAQAQPQPPPPHPPTHALEKQL 145
            .:|::.|:                                 :|.....|.||||..|..||:..|
Human    43 GYPMFMPY---------------------------------RPVVLPPPPPPPPALPQAALQPAL 74

  Fly   146 PPTLPH----PLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQHM-AAAGRMH 205
            ||..||    .|.|.|.  :..|.|:|   |:...:|.|..       ...|..||. |||.|..
Human    75 PPAHPHHQIPSLPTGFC--SSLAQGMA---LTSTLMATLPG-------GFSASPQHQEAAAARKF 127

  Fly   206 EDQANPGMAQLQEPTPPQAHSSP-----AKSGSHSPMEPALDV---------------------- 243
            ..|..||.....:....||.:..     ||.||......|..|
Human   128 APQPLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRGQGKDESKVEDDP 192

  Fly   244 -GMDEDFECSGDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKD 307
             |.:|.|....|.           :|:.:.:.:...|:...|.....::....|    |..|...
Human   193 KGKEESFSLESDV-----------DYSSDDNLTGQAAHKEEDPGHALEETPPSS----GAAGSTT 242

  Fly   308 SQGNGSSSNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRA 372
            |.|       |:||||||||||||||||:|||.|||||||||||||.:|||||||||||||||||
Human   243 STG-------KNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRA 300

  Fly   373 KWKRVKAGLTSHGLGRNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEK 419
            ||||||||..:...|.  .:...||||||||||:|||:||||||||:
Human   301 KWKRVKAGNANSKTGE--PSRNPKIVVPIPVHVSRFAIRSQHQQLEQ 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	46/50 (92%)
GBX2	NP_001476.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	59..81		11/21 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..139		10/27 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..251		15/93 (16%)
		Homeobox	250..303	CDD:306543	48/52 (92%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160114
Domainoid	1	1.000	108	1.000	Domainoid score	I6426
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	175	1.000	Inparanoid score	I4061
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003648
OrthoInspector	1	1.000	-	-		otm42097
orthoMCL	1	0.900	-	-		OOG6_106620
Panther	1	1.100	-	-	O	PTHR24334
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4817
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.780