DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and Gbx1

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001258382.1	Gene:	Gbx1 / 246149	RGDID:	621864	Length:	425	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	162/466 - (34%)
Similarity:	190/466 - (40%)	Gaps:	126/466 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 TPATATPPSPPEERDQE------QEAEQEQELS--ARAMVASSALGLTQFPLYNPWLHGYFAQNH 97
            ||:....|.||.||...      .|....:.|.  ||:....||.|..:.|             .
  Rat     7 TPSPPARPLPPYERGSAAPEPHCAEPAPRRYLGPRARSEPCVSAPGARRGP-------------G 58

  Fly    98 ERLTHLIAGGCYLPSSPAGHPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLPH-PLDTRFLPFN 161
            ..:.....||....|..:|..........:...||||. ..|.|....|..:|: ||      ..
  Rat    59 SAMQRAAGGGAPGGSGGSGGGPGTAFSIDSLIGPPPPR-SGHLLYTGYPMFMPYRPL------VL 116

  Fly   162 PAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPGMAQLQE--PT---P 221
            |.|...||.......||.|        .|...||.:...||.   .||.|.|..|..  |:   |
  Rat   117 PQALAPAPLPAGLPPLAPL--------ASFAGRLSNTFCAGL---GQAVPSMVALTTALPSFAEP 170

  Fly   222 PQAHSSP-----------AKSGSHSPMEP-------ALDVG----------------------MD 246
            |.|:..|           |.:.|.|..||       |||..                      ..
  Rat   171 PDAYYGPPELAAAAAAAAASTVSRSNPEPPARRTDGALDADELLPAREKVTEPPPPPPPPPPHFS 235

  Fly   247 EDFECSGDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSR-----HEGGGMGG- 305
            |.|.         ||....:.|:.:.:|....|...:.||...:..|..|.     ...||.|.
  Rat   236 ETFP---------SLPAEGKVYSSDEEKLEPPAGEPAGSEPEEEGSGGDSEDSFLDSSAGGPGAL 291

  Fly   306 -------KDSQGNGSSSNS-----------KSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQI 352
                   |.|.|.|:...:           ||||||||||||||||||:|||.||||||||||||
  Rat   292 LGPKPKLKGSLGTGAEEGTPVATGVTTPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQI 356

  Fly   353 ATSLKLSEVQVKIWFQNRRAKWKRVKAGLTSHGLGRNG-TTSGTKIVVPIPVHVNRFAVRSQHQQ 416
            |.:|||||||||||||||||||||:|||..|   .|:| .....|||||||||||||||||||||
  Rat   357 AHALKLSEVQVKIWFQNRRAKWKRIKAGNVS---SRSGEPVRNPKIVVPIPVHVNRFAVRSQHQQ 418

  Fly   417 LEKMCLSGPKP 427
            :|:    |.:|
  Rat   419 MEQ----GARP 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	46/50 (92%)
Gbx1	NP_001258382.1	Homeobox	326..379	CDD:278475	48/52 (92%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354182
Domainoid	1	1.000	108	1.000	Domainoid score	I6303
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I3943
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003648
OrthoInspector	1	1.000	-	-		otm46247
orthoMCL	1	0.900	-	-		OOG6_106620
Panther	1	1.100	-	-	LDO	PTHR24334
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.750