DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment unpg and gbx2

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_694496.1	Gene:	gbx2 / 245948	ZFINID:	ZDB-GENE-020509-2	Length:	342	Species:	Danio rerio

Alignment Length:	358	Identity:	145/358 - (40%)
Similarity:	188/358 - (52%)	Gaps:	86/358 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 LIAGGCYLPSSPA-------GHPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLP-HPLDTRFLP 159
            ||.|    |..|:       |:|.....::...|.||||.||| ..:..||.|.| ||     :|
Zfish    27 LIGG----PPQPSPGHFVYTGYPMFMPYRSVVLPPPPPPPPPT-LPQSALPTTHPHHP-----IP 81

  Fly   160 FNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPGMAQLQ---EPTP 221
            ..|::                    :..||:     |.||....:        ||.|.   ..:|
Zfish    82 GLPSS--------------------FCSSLA-----QGMALTSTL--------MATLPGGFSSSP 113

  Fly   222 PQAHSSPA-KSGS---HSPMEPALDVGMD-EDFE--CSGDSCSDISL-------TMSPRNYNGEM 272
            .|.|...| |.||   |:..:.:.|:.:| ||.:  .:.||.|..|.       |.:.|.::.:.
Zfish   114 SQQHQDAARKLGSQSIHAMFDKSQDIRLDGEDGKTFATKDSTSIPSFHDSQSVHTSTVRGHSKDD 178

  Fly   273 DKS-----RNGAYT-NSDSEDCSDDEGAQS----RHEGGGMGGKDS---QGNG---SSSNSKSRR 321
            .|.     ::.::: :||.:..|||.|..:    :.:|.|.||.|.   .|||   ::|..|:||
Zfish   179 SKEDDCHRKDESFSMDSDLDYSSDDNGPGNAMCQKEDGDGSGGLDDGVHGGNGAGNTTSTGKNRR 243

  Fly   322 RRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKAGLTSHGL 386
            ||||||||||||||:|||.|||||||||||||.:|||||||||||||||||||||||||..:...
Zfish   244 RRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNVNSKT 308

  Fly   387 GRNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEK 419
            |.  .:...||||||||||:|||:||||||||:
Zfish   309 GE--PSRNPKIVVPIPVHVSRFAIRSQHQQLEQ 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	46/50 (92%)
gbx2	NP_694496.1	Homeobox	244..297	CDD:278475	48/52 (92%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596437
Domainoid	1	1.000	108	1.000	Domainoid score	I6383
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	174	1.000	Inparanoid score	I4063
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003648
OrthoInspector	1	1.000	-	-		otm26136
orthoMCL	1	0.900	-	-		OOG6_106620
Panther	1	1.100	-	-	O	PTHR24334
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4817
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.780