DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and Vax1

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_033527.1	Gene:	Vax1 / 22326	MGIID:	1277163	Length:	338	Species:	Mus musculus

Alignment Length:	318	Identity:	79/318 - (24%)
Similarity:	112/318 - (35%)	Gaps:	120/318 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 GEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGG------KDSQG-----------NGSSSNS 317
            |:.||.....::::::...|.:...:||...|..|.      |:.||           |.|.|||
Mouse     3 GKPDKMDVRCHSDTEAARVSKNAHKESREIKGAEGSLPAAFLKEPQGAFSGSGASEDCNKSKSNS 67

  Fly   318 -------------------------------KSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQ 351
                                           :.:|.||:||:|||..||.||...:|:...||::
Mouse    68 SADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTE 132

  Fly   352 IATSLKLSEVQVKIWFQNRRAKWKRVKAGLTSHGLGRNGTTSGTKIVVPIPVHVNRFAVRSQHQQ 416
            :|..|.|||.|||:||||||.|.|:           ..|..|..:.||.     ...|..|..:.
Mouse   133 LARQLNLSETQVKVWFQNRRTKQKK-----------DQGKDSELRSVVS-----ETAATCSVLRL 181

  Fly   417 LEKMCLSGPK--PDLRKKLSAEAIG-----------GFEKFSGSTNAS----------------- 451
            ||:..|..|.  |.|....:..|:|           |....:||..|:
Mouse   182 LEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAAAATAPGPAGAASQ 246

  Fly   452 -------SPSGGPVGLGVGVGVGVGVG------------LG------VSTPLSLARSI 484
                   :|..||.|.| |:..|....            ||      .|.||::|.|:
Mouse   247 HQPAVGGAPGPGPAGPG-GLHAGAPTASHGLFSLPVPSLLGSVASRLSSAPLTMAGSL 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	28/50 (56%)
Vax1	NP_033527.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..69		16/65 (25%)
		Homeobox	103..156	CDD:306543	29/52 (56%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	239..269		6/30 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	318..338
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910