DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and Shox2

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_038693.1	Gene:	Shox2 / 20429	MGIID:	1201673	Length:	331	Species:	Mus musculus

Alignment Length:	167	Identity:	50/167 - (29%)
Similarity:	65/167 - (38%)	Gaps:	52/167 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 GAQSRHEGGGMGG-----------------------------------KDSQG--NGSSSNSKSR 320
            ||.....|||.||                                   .|::|  :...:..|.|
Mouse    77 GAGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPELKDRKDDAKGMEDEGQTKIKQR 141

  Fly   321 RRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKAGLTSHG 385
            |.||.||.|||.||||.|....|.....|.:::..|.|||.:|::||||||||.::.:..|
Mouse   142 RSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQL---- 202

  Fly   386 LGRNGTTSGTKI------VVPIPVHVNRFAVRSQHQQ 416
              ..|...|...      |.|   :||..|:|...||
Mouse   203 --HKGVLIGAASQFEACRVAP---YVNVGALRMPFQQ 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	26/50 (52%)
Shox2	NP_038693.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..140		9/62 (15%)
		Homeobox	143..197	CDD:395001	27/53 (51%)
		OAR	311..327	CDD:397759
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	313..326
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910