Protein Alignment unpg and EN1

DIOPT Version :9

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001417.3
• Gene: EN1 / 2019
• HGNCID: 3342
• Length: 392
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 108/454 - (23%)
• Similarity: 145/454 - (31%)
• Gaps: 183/454 - (40%)

  Fly    52 EERDQEQEAEQEQELSARAMVASSALGLTQFPLYNPWLHGYFAQNHERLTHLIAGGCYLPSSPAG 116
            ||:..|.:::::..|.|.|......|.|:..|       |             |.|    ||.:|
Human     2 EEQQPEPKSQRDSALGAAAAATPGGLSLSLSP-------G-------------ASG----SSGSG 42

  Fly   117 HPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELM 181
            ......|   ..|||.||.||....   |||...||    .||.:|.    .|..
Human    43 SDGDSVP---VSPQPAPPSPPAAPC---LPPLAHHP----HLPPHPP----PPPP---------- 83

  Fly   182 NQDYVHSLSVHARLQHMAA-------AGRMH-------EDQANPGMAQLQEPTPPQAHSSPAKSG 232
                          ||:||       |.::|       ::...|.....:|..|||...:.|..|
Human    84 --------------QHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKEQPPPQLLVAAAARG 134

  Fly   233 -----------------SHSPMEP-------ALDVGMDEDFECSGDSCSDISLTMSPRNYNGEMD 273
                             ...|:.|       |..:....|..|.....|      .|........
Human   135 GAGGGGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGPPDGS------QPAAAGAGAS 193

  Fly   274 KSRN------------GAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQG---------------- 310
            |:.|            .|...:.:...||..|..|   |||.|...:||
Human   194 KAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGGGGS---GGGAGSPGAQGTKYPEHGNPAILLMGS 255

  Fly   311 -NGS--------------------------SSNSKSR------------RRRTAFTSEQLLELER 336
             ||.                          ||..::|            |.|||||:|||..|:.
Human   256 ANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKNEKEDKRPRTAFTAEQLQRLKA 320

  Fly   337 EFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR---VKAGLTSH----GLGRNGTTS 393
            ||.|.:|::...|..:|..|.|:|.|:||||||:|||.|:   :|.||..|    ||..:.||:
Human   321 EFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTT 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	27/50 (54%)
EN1	NP_001417.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..100		37/159 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..164		3/31 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..251		10/34 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..306		3/23 (13%)
		Homeobox	306..359	CDD:278475	28/52 (54%)
		Engrail_1_C_sig	361..390	CDD:287495	8/24 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910