Protein Alignment unpg and DLX4

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 76/316 - (24%)
• Similarity: 112/316 - (35%)
• Gaps: 103/316 - (32%)

  Fly   132 PPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQ 196
            |.|.|...|.:...|...|.|......|...:....|..:|||.|       .|.|.||.
Human     5 PCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSR-------PYGHLLSY----- 57

  Fly   197 HMAAAGRMHEDQANPGMAQL--QEPTPPQAHSSPAKSGSHSPMEPALDVGMDEDFECSGDSCSDI 259
                   .:.:.||||.:.|  |:|.   |.|.|....:..|.|      ::.|.|
Human    58 -------PYTEPANPGDSYLSCQQPA---ALSQPLCGPAEHPQE------LEADSE--------- 97

  Fly   260 SLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRRRRT 324
                .||                                    :..:.|:....:...|.|:.||
Human    98 ----KPR------------------------------------LSPEPSERRPQAPAKKLRKPRT 122

  Fly   325 AFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKAGLTSHGLGRN 389
            .::|.||..|.:.|...:||:|.||:|:|..|.|::.||||||||:|:|:|::   |..:..|:.
Human   123 IYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKL---LKQNSGGQE 184

  Fly   390 GTTSGTKIVV-----PIPV--------------HVNRFAVRSQHQQLEKMCLSGPK 426
            |...|....|     |:|.              :.|.|....||...:  .|:.|:
Human   185 GDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSD--VLASPQ 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	25/51 (49%)
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		10/94 (11%)
		Homeodomain	118..174	CDD:459649	27/55 (49%)