Protein Alignment unpg and NKX2-3

DIOPT Version :9

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_660328.2
• Gene: NKX2-3 / 159296
• HGNCID: 7836
• Length: 364
• Species: Homo sapiens
• Alignment Length: 406
• Identity: 96/406 - (23%)
• Similarity: 133/406 - (32%)
• Gaps: 141/406 - (34%)

  Fly   149 LPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQ-DYVHSLSVHARLQH--------MAAA--- 201
            ||.|              |..|..|.:.:..|..| .:.|...:.|.|:|        :|||
Human     3 LPSP--------------VTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGT 53

  Fly   202 -----GRMHEDQANPGMAQLQEPTPPQAHSSPAKSG------SHSPMEPALDVGMDEDFECSGDS 255
                 |...|:.....::.|........|..   ||      .|:.:.               ||
Human    54 QFSDGGEEDEEDEGEKLSYLNSLAAADGHGD---SGLCPQGYVHTVLR---------------DS 100

  Fly   256 CSDISLTMSPRNYNGE----MDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSN 316
            ||:      |:.:..|    .|:|:.........|...|.:.|:               ......
Human   101 CSE------PKEHEEEPEVVRDRSQKSCQLKKSLETAGDCKAAE---------------ESERPK 144

  Fly   317 SKSRRR-RTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKAG 380
            .:|||: |..|:..|:.||||.|..::|||..||..:|:||||:..||||||||||.|.||.:..
Human   145 PRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQD 209

  Fly   381 ----LTSHG------------LGRNG----TTSGTKIVVPIPVHVNRFAVRSQHQQLEKMCLSGP 425
                |.:|.            |.|:|    |.|......|..|..:.::..           |.|
Human   210 KSLELGAHAPPPPPRRVAVPVLVRDGKPCVTPSAQAYGAPYSVGASAYSYN-----------SFP 263

  Fly   426 KPDLRKKLSAEAI------------------------GGFEKFSGSTNASSPSGGPVGLGVGVGV 466
            ........:|.|.                        ||....|.:|.|..|:....|.|..|.|
Human   264 AYGYGNSAAAAAAAAAAAAAAAAYSSSYGCAYPAGGGGGGGGTSAATTAMQPACSAAGGGPFVNV 328

  Fly   467 ----GVGVGLGVSTPL 478
                |.|.| |.:.||
Human   329 SNLGGFGSG-GSAQPL 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	28/50 (56%)
NKX2-3	NP_660328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..153		5/35 (14%)
		HOX	148..204	CDD:197696	31/55 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910