DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and Hoxa4

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_032291.1	Gene:	Hoxa4 / 15401	MGIID:	96176	Length:	285	Species:	Mus musculus

Alignment Length:	317	Identity:	84/317 - (26%)
Similarity:	121/317 - (38%)	Gaps:	101/317 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 LTQFPLYNPWLHGYFAQNHERLTHLIAGGCYLPSSPAGHPAAQQPQAQAQPQPPPPH----PPTH 139
            ::.|.:.:.::...|....|...|...||.  ..:..|.|...:||:......|.||    ||.:
Mouse     3 MSSFLINSNYIEPKFPPFEEFAPHGGPGGG--DGAVGGGPGYPRPQSAPHLPAPNPHAARQPPAY 65

  Fly   140 ALEKQLPPTLP---HPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQHMAAA 201
            ...:...|:.|   :|......|:  |..|.:|                       ||.:...|.
Mouse    66 YAPRAREPSYPGGLYPAPAAACPY--ACRGASP-----------------------ARPEQSPAP 105

  Fly   202 GRMHEDQANPGMAQLQEPTPPQAHSSPAKSGSHSPMEPALDVGMDEDFECSGDSCSDISLTMSPR 266
            |      |:|..|. |.|.||: |.:|      .|..||:         .:|.|.....|.::
Mouse   106 G------AHPSPAP-QPPAPPR-HCAP------GPTTPAV---------ATGGSAPACPLLLA-- 145

  Fly   267 NYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKD------------SQGNGSSSNSKS 319
                                    |:|.      .|..||:            |..|.|.:..:.
Mouse   146 ------------------------DQGP------AGPKGKEPVVYPWMKKIHVSAVNSSYNGGEP 180

  Fly   320 RRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR 376
            :|.|||:|.:|:||||:|||..:||:...|.:||.:|.|||.||||||||||.|||:
Mouse   181 KRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKK 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	31/50 (62%)
Hoxa4	NP_032291.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..70		13/52 (25%)
		Antp-type hexapeptide	159..164		0/4 (0%)
		Homeobox	183..236	CDD:278475	32/52 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	238..285		84/317 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810