DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and CPHXL

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001342542.1	Gene:	CPHXL / 105371346	HGNCID:	51815	Length:	405	Species:	Homo sapiens

Alignment Length:	180	Identity:	40/180 - (22%)
Similarity:	61/180 - (33%)	Gaps:	39/180 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   301 GGMGGKDSQGN--GSSSNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQV 363
            ||...::...|  ..:.|.:..:.|..|:.|.|.||:..|....|...|.|..:|.........:
Human     8 GGFPAEEDHHNEERQTKNKRKTKHRHKFSEELLQELKEIFGENCYPDYTTRKTLAIKFDCPVNVI 72

  Fly   364 KIWFQNRRAKW-----KRVKAGLTSHGLGRNGTTSGTKIVVPIPVHVNRF-----AVRSQHQQLE 418
            ..||||:||:.     :|:......|               ..||..:.|     ...:.|....
Human    73 DNWFQNKRARLPPAERRRIFVLQKKH---------------DFPVQAHSFLSCQETQAAAHNYAT 122

  Fly   419 KMCLSGPKPDLRKKLSAEAIG---------GFEKFSGSTNASSPSG--GP 457
            |..|||.:..|.::.....:.         |:..|| ..|..:||.  ||
Human   123 KQSLSGAQRALMRRAGCSHLEKQWIPSQEMGYNCFS-LENQETPSQQVGP 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	16/55 (29%)
CPHXL	NP_001342542.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..33		4/24 (17%)
		HOX	28..82	CDD:197696	16/53 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	340..363
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910