Protein Alignment unpg and HOXB13

DIOPT Version :9

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_006352.2
• Gene: HOXB13 / 10481
• HGNCID: 5112
• Length: 284
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 76/296 - (25%)
• Similarity: 114/296 - (38%)
• Gaps: 41/296 - (13%)

  Fly    94 AQNHERLTHLIAGGCYLPSSP-AGHPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLPHPLDTRF 157
            |::.|.|.....|...:..|| ..||||           |...|..:.....||.:...|.....
Human    12 AKDIEGLLGAGGGRNLVAHSPLTSHPAA-----------PTLMPAVNYAPLDLPGSAEPPKQCHP 65

  Fly   158 LPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPGMAQLQEPTPP 222
            .|..|.....||....|      ....|.......:.|:..|.|..:....|....|..:.|:.|
Human    66 CPGVPQGTSPAPVPYGY------FGGGYYSCRVSRSSLKPCAQAATLAAYPAETPTAGEEYPSRP 124

  Fly   223 QAHS-SPAKSGSHSPMEPALDVGMDEDFECSGDSCSDISLTMSPRNYNGEMDKSRNGAYTNS-DS 285
            ...: .|...|::.||...|||.:.:.....|:...|..|         .:|..::.|.... :|
Human   125 TEFAFYPGYPGTYQPMASYLDVSVVQTLGAPGEPRHDSLL---------PVDSYQSWALAGGWNS 180

  Fly   286 EDCSDDEGAQSRHEGGGMGGK----DSQGN---GSSSNSKSRRRRTAFTSEQLLELEREFHAKKY 343
            :.|     .|......|...|    ||.|.   .:.:..:.|::|..::..||.|||||:.|.|:
Human   181 QMC-----CQGEQNPPGPFWKAAFADSSGQHPPDACAFRRGRKKRIPYSKGQLRELEREYAANKF 240

  Fly   344 LSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKA 379
            ::..:|.:|:.:..|||.|:.|||||||.|.|:|.|
Human   241 ITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLA 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	23/50 (46%)
HOXB13	NP_006352.2	HoxA13_N	12..121	CDD:372013	26/125 (21%)
		HOX	216..272	CDD:197696	25/55 (45%)
		Interaction with DNA. /evidence=ECO:0000305|PubMed:28473536, ECO:0000305|Ref.8	217..246		11/28 (39%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000305|PubMed:28473536	258..269		7/10 (70%)
		Interaction with DNA. /evidence=ECO:0000305|PubMed:28473536, ECO:0000305|Ref.8	270..273		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910