DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and CDX4

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_005184.1	Gene:	CDX4 / 1046	HGNCID:	1808	Length:	284	Species:	Homo sapiens

Alignment Length:	211	Identity:	56/211 - (26%)
Similarity:	78/211 - (36%)	Gaps:	91/211 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 TNSDSEDCSDDEGAQSRHEGGGMGGKD--SQGNGS-----------SSNSKSR------------ 320
            |:|.:..||.|. :.....|||..|..  .|..||           ||.|:||
Human   102 TSSPAAFCSTDY-SNLGPVGGGTSGSSLPGQAGGSLVPTDAGAAKASSPSRSRHSPYAWMRKTVQ 165

  Fly   321 ---------RRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR 376
                     :.|..:|..|.||||:|||..:|:::..:|::|.:|.|||.||||||||||||.::
Human   166 VTGKTRTKEKYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERK 230

  Fly   377 VKAGLTSHGLGRNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEKMCLSGPKPDLRKKLSAEAIGGF 441
            :                                                   ::||:|.     |
Human   231 M---------------------------------------------------IKKKISQ-----F 239

  Fly   442 EKFSGSTNASSPSGGP 457
            |...||..:.|.|..|
Human   240 ENSGGSVQSDSDSISP 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	28/50 (56%)
CDX4	NP_005184.1	Caudal_act	13..162	CDD:309740	17/60 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	15..40
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	120..155		12/34 (35%)
		Homeobox	177..229	CDD:306543	29/51 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	238..259		7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910