DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unpg and Hoxa1

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_037207.2	Gene:	Hoxa1 / 103690132	RGDID:	11414885	Length:	334	Species:	Rattus norvegicus

Alignment Length:	415	Identity:	107/415 - (25%)
Similarity:	144/415 - (34%)	Gaps:	146/415 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 AMVASSALGLTQF----------------------PLYNPWLHGYFAQNHERLTHLIAGG---CY 109
            |.|.||..|:|.|                      .:.:|..|.:...:.:..|:..:|.   .|
  Rat    25 ARVYSSDHGITTFQSCAVSANSCGGDDRFLGGRGVQITSPHHHHHHHHHPQPATYQTSGNLGVSY 89

  Fly   110 LPSSPAGHPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSY 174
            ..||......||...|        |:.| :.|.::...:..:|         |.|..|...:||
  Rat    90 SHSSCGPSYGAQNFSA--------PYGP-YGLNQEADVSGGYP---------PCAPAVYSGNLS- 135

  Fly   175 RRLAELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPGMAQLQEPTPPQAHSSPAKSGSHSPMEP 239
                ..|.|.:.|         |...||      ...|..|....:..|.|.|.|.:..::.:.|
  Rat   136 ----SPMVQHHHH---------HQGYAG------GTVGSPQYIHHSYGQEHQSLALATYNNSLSP 181

  Fly   240 ALDVGMDEDFECSGDSC-SDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGM 303
             |.....|       :| |..|.|.||......|...||...|                   |.:
  Rat   182 -LHASHQE-------ACRSPASETSSPAQTFDWMKVKRNPPKT-------------------GKV 219

  Fly   304 G--GKDSQGNGSSSNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIW 366
            |  |...|.|..         ||.||::||.|||:|||..|||:...|.:||.||:|:|.|||||
  Rat   220 GEYGYVGQPNAV---------RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIW 275

  Fly   367 FQNRRAKW-KRVKAGLTSHGLGRNGTTSGTKIVVPI-PVHVNRFAVRSQHQQLEKMCLSGPKPDL 429
            |||||.|. ||.|.||                 :|| |.                   :.|..|.
  Rat   276 FQNRRMKQKKREKEGL-----------------LPISPA-------------------TPPGSDE 304

  Fly   430 RKKLSAEAIGGFEKFSGSTNASSPS 454
            :.:.|:      ||.|.|.:|.||:
  Rat   305 KTEESS------EKSSSSPSAPSPA 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	32/51 (63%)
Hoxa1	NP_037207.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	61..82		3/20 (15%)
		Interaction with OGT. /evidence=ECO:0000250\|UniProtKB:P09022	74..202		38/173 (22%)
		COG5576	175..>285	CDD:227863	51/145 (35%)
		Antp-type hexapeptide	203..208		0/4 (0%)
		Homeobox	232..284	CDD:278475	33/51 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..334		20/86 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910