DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment unpg and hoxa3

DIOPT Version :9

Sequence 1:	NP_477146.1	Gene:	unpg / 35942	FlyBaseID:	FBgn0015561	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001120901.1	Gene:	hoxa3 / 100151729	XenbaseID:	XB-GENE-482267	Length:	406	Species:	Xenopus tropicalis

Alignment Length:	327	Identity:	86/327 - (26%)
Similarity:	136/327 - (41%)	Gaps:	71/327 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 HALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQHMAAAGR 203
            :|.::|.||: ...|:|.:  ..||.:..:|........|..:|:..:.:::..:.     .|..
Frog    27 NASQQQYPPS-SSLLETEY--HRPACSLQSPGSAVPHHKANDINESCMRTINSQSN-----QAPV 83

  Fly   204 MHEDQANPGMAQLQEP----TPPQAHSSPAKSGSHSPMEPALDVGMDEDFECSGDSCSDISLTMS 264
            :.|.|..|     |.|    :|||..|:.|.:.|:.                   :.|..|.|||
Frog    84 IPEQQPTP-----QGPPPSVSPPQTTSNAATASSNK-------------------ATSITSPTMS 124

  Fly   265 PRNYNGEMDKSRNG-----AYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRRRRT 324
            .:.:.. |.:||..     |.::|..|.|:.|:....:                   |.|:|.||
Frog   125 KQIFPW-MKESRQNTKQQKAGSSSSGESCAGDKSPPGQ-------------------SSSKRART 169

  Fly   325 AFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKAG---LTSHGL 386
            |:||.||:|||:|||..:||....|.::|..|.|:|.|:||||||||.|:|:.:.|   :||.|
Frog   170 AYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKSMMTSSG- 233

  Fly   387 GRNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEKMCLSGPKPDLRKKLSAEAIGGFEKFSGSTNAS 451
            |::...|      |:|.......:.|.|..:..:......|....|....|.|....:....|:.
Frog   234 GQSPCRS------PVPTPSVGGYLNSMHSLVNSVPYEPQSPPAFNKHHPSAYGVPAPYPSPHNSC 292

  Fly   452 SP 453
            .|
Frog   293 PP 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeobox	324..375	CDD:278475	29/50 (58%)
hoxa3	NP_001120901.1	Homeobox	168..221	CDD:395001	30/52 (58%)
hoxa3	NP_001120901.1	DUF4074	344..404	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910