DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8026 and FLX1

DIOPT Version :9

Sequence 1:	NP_724769.2	Gene:	CG8026 / 35941	FlyBaseID:	FBgn0033391	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_012132.3	Gene:	FLX1 / 854672	SGDID:	S000001396	Length:	311	Species:	Saccharomyces cerevisiae

Alignment Length:	310	Identity:	98/310 - (31%)
Similarity:	164/310 - (52%)	Gaps:	36/310 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EHLVAGVSGGVVSTLILHPLDLIKIRFAVNDGRTATVPQYRGLSSAFTTIFRQEGFRG------L 82
            :.:::|:|.|.|:||::|||||:|:|..::  .|:....:.|.......|.|.....|      |
Yeast    11 KEVISGLSAGSVTTLVVHPLDLLKVRLQLS--ATSAQKAHYGPFMVIKEIIRSSANSGRSVTNEL 73

  Fly    83 YKGVTPNVWGSGSSWGLYFMFYNTIK------------TFIQGGNTTMPLGPTMNMLAAAESGIL 135
            |:|::.|::|:..:||:||..|...|            |.::|......:...:.:.|.|.||::
Yeast    74 YRGLSINLFGNAIAWGVYFGLYGVTKELIYKSVAKPGETQLKGVGNDHKMNSLIYLSAGASSGLM 138

  Fly   136 TLLLTNPIWVVKTRLCLQCDAASSAEYRGMIHALGQIYKEEGIRGLYRGFVPGMLGVSHGAIQFM 200
            |.:|||||||:|||:......|..| |..|.:.:.|:.:.:|.:||::|.||.:.|||.||:.|.
Yeast   139 TAILTNPIWVIKTRIMSTSKGAQGA-YTSMYNGVQQLLRTDGFQGLWKGLVPALFGVSQGALYFA 202

  Fly   201 TYEELKNAYNEYRKL------PIDTKLATTEYLAFAAVSKLIAAAATYPYQVVRARLQD---HHH 256
            .|:.||.     |||      .:|..|...|.:...::.|:::....||:|::::.||.   :..
Yeast   203 VYDTLKQ-----RKLRRKRENGLDIHLTNLETIEITSLGKMVSVTLVYPFQLLKSNLQSFRANEQ 262

  Fly   257 RYNGTWDCIKQTWRFEGYRGFYKGLKASLTRVVPACMVTFLVYENVSHFL 306
            ::. .:..||.....:|:.|.||||.|:|.|.:|:..:||.||||:.|.|
Yeast   263 KFR-LFPLIKLIIANDGFVGLYKGLSANLVRAIPSTCITFCVYENLKHRL 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8026	NP_724769.2	PTZ00169	13..287	CDD:240302	88/289 (30%)
		Mito_carr	23..115	CDD:278578	31/108 (29%)
		Mito_carr	119..213	CDD:278578	35/93 (38%)
		Mito_carr	220..307	CDD:278578	28/90 (31%)
FLX1	NP_012132.3	Mito_carr	5..105	CDD:395101	29/95 (31%)
		Mito_carr	122..215	CDD:395101	38/98 (39%)
		Mito_carr	223..311	CDD:395101	27/88 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343965
Domainoid	1	1.000	76	1.000	Domainoid score	I2129
eggNOG	1	0.900	-	-		E1_KOG0764
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6151
Inparanoid	1	1.050	169	1.000	Inparanoid score	I1018
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53601
OrthoFinder	1	1.000	-	-		FOG0002021
OrthoInspector	1	1.000	-	-		oto99320
orthoMCL	1	0.900	-	-		OOG6_100767
Panther	1	1.100	-	-	LDO	PTHR45683
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1725
SonicParanoid	1	1.000	-	-		X1155
TreeFam	1	0.960	-	-
	15	14.790