Protein Alignment CG8026 and SLC25A19

DIOPT Version :10

• Sequence 1: NP_724769.2
• Gene: CG8026 / 35941
• FlyBaseID: FBgn0033391
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_068380.3
• Gene: SLC25A19 / 60386
• HGNCID: 14409
• Length: 320
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 81/304 - (26%)
• Similarity: 138/304 - (45%)
• Gaps: 24/304 - (7%)

  Fly    20 HVKYEHLVAGVSGGVVSTLILHPLDLIKIRFAVND---GRTATVPQYRGLSSAFTTIFRQEGFRG 81
            :.|::..|||...|:|:..::.|.|:|||||.:..   .|:....:|.|:..|...|.::||...
Human    13 NTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTA 77

  Fly    82 LYKGVTPNVWGSGSSWGLYFMFYNTIKTFIQGGNTTMPLGPTMNMLAAAESGILTLLLTNPIWVV 146
            .:||..|....|.....:.|:.:..:...:..|:.......:::.:....:..:..|..:|:.|:
Human    78 FWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVL 142

  Fly   147 KTRLCLQCDAASSAEYRGMIHALGQIYKEEGIRGLYRGFVPGMLGV-SHGAIQFMTYEELKNAYN 210
            :||...|   .....|..:.||:|.:|:.||.:..|:|..|.::.: .:..:||..|..||:.|.
Human   143 RTRFAAQ---GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYK 204

  Fly   211 EYRKLPID-TKLATTEYLAFAAVSKLIAAAATYPYQVVRARLQ----DHH-------HRYNGTWD 263
              ..:|.: .|....:.|...:.:.:|:...|||..:.:.|||    :|.       .||.|..|
Human   205 --WAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMD 267

  Fly   264 CIKQTWRFEGYRGFYKGLKASLTRVVPACMVTFLVYE---NVSH 304
            |.||..:.||..||:|||..||.:...:....|..||   ||.|
Human   268 CAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEFFCNVFH 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8026	NP_724769.2	Mito_carr	23..115	CDD:395101	24/94 (26%)
		Mito_carr	119..213	CDD:395101	22/94 (23%)
		Mito_carr	220..307	CDD:395101	32/99 (32%)
SLC25A19	NP_068380.3	Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	13..106		25/92 (27%)
		PTZ00169	20..293	CDD:240302	74/277 (27%)
		Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	116..202		21/88 (24%)
		Mito_carr	118..203	CDD:395101	21/87 (24%)
		Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	214..309		28/94 (30%)
		Substrate recognition. /evidence=ECO:0000250	241..246		2/4 (50%)