DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8026 and aralar1

DIOPT Version :9

Sequence 1:	NP_724769.2	Gene:	CG8026 / 35941	FlyBaseID:	FBgn0033391	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001247368.1	Gene:	aralar1 / 43616	FlyBaseID:	FBgn0028646	Length:	707	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	92/316 - (29%)
Similarity:	140/316 - (44%)	Gaps:	44/316 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IKAQSTGSPKKFNVFAHV---KYEHLVAGVSGGVVSTLILHPLDLIKIRFAVNDGRTATVPQ--Y 63
            |||  ..||...:.|..|   .|...:...:|.|.:| :::|:||:|.|.. |....:.:.:  |
  Fly   336 IKA--VESPADRSAFIQVLESSYRFTLGSFAGAVGAT-VVYPIDLVKTRMQ-NQRAGSYIGEVAY 396

  Fly    64 RGLSSAFTTIFRQEGFRGLYKGVTPNVWGSGSSWGLYFMFYNTIKTFI--QGGNTTMPLGPT-MN 125
            |.....|..:.|.|||.|||:|:.|.:.|......:.....:.::..:  :.||.     || ..
  Fly   397 RNSWDCFKKVVRHEGFMGLYRGLLPQLMGVAPEKAIKLTVNDLVRDKLTDKKGNI-----PTWAE 456

  Fly   126 MLAAAESGILTLLLTNPIWVVKTRLCLQCDAASSAEYRGMIHALGQIYKEEGIRGLYRGFVPGML 190
            :||...:|...::.|||:.:||.||.:..:.||.::.|..     .:.:|.|:.|||:|....:|
  Fly   457 VLAGGCAGASQVVFTNPLEIVKIRLQVAGEIASGSKIRAW-----SVVRELGLFGLYKGARACLL 516

  Fly   191 -GVSHGAIQFMTYEEL------KNAYNEYRKLPIDTKLATTEYLAFAAVSKLIAAAATYPYQVVR 248
             .|...||.|.||...      |:.||....|           ||..|::.:.||:...|..|::
  Fly   517 RDVPFSAIYFPTYAHTKAMMADKDGYNHPLTL-----------LAAGAIAGVPAASLVTPADVIK 570

  Fly   249 ARLQ----DHHHRYNGTWDCIKQTWRFEGYRGFYKGLKASLTRVVPACMVTFLVYE 300
            .|||    .....|.|.||..|:....||.|.|:||..|.:.|..|...||.:.||
  Fly   571 TRLQVVARSGQTTYTGVWDATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYE 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8026	NP_724769.2	PTZ00169	13..287	CDD:240302	81/292 (28%)
		Mito_carr	23..115	CDD:278578	23/95 (24%)
		Mito_carr	119..213	CDD:278578	31/101 (31%)
		Mito_carr	220..307	CDD:278578	28/85 (33%)
aralar1	NP_001247368.1	EF-hand_7	35..99	CDD:290234
		EF-hand_8	51..99	CDD:290545
		EF-hand_7	81..134	CDD:290234
		EFh	84..135	CDD:298682
		EF-hand_7	111..173	CDD:290234
		Mito_carr	350..448	CDD:278578	24/99 (24%)
		PTZ00169	358..631	CDD:240302	84/292 (29%)
		Mito_carr	449..539	CDD:278578	30/99 (30%)
		Mito_carr	544..633	CDD:278578	29/94 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441778
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840