DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8026 and slc25a32a

DIOPT Version :9

Sequence 1:	NP_724769.2	Gene:	CG8026 / 35941	FlyBaseID:	FBgn0033391	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_956550.1	Gene:	slc25a32a / 393226	ZFINID:	ZDB-GENE-040426-758	Length:	324	Species:	Danio rerio

Alignment Length:	312	Identity:	177/312 - (56%)
Similarity:	231/312 - (74%)	Gaps:	12/312 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IKAQSTGSPKKFNVFA-------HVKYEHLVAGVSGGVVSTLILHPLDLIKIRFAVNDGRTATVP 61
            :.|.|:||  .|::.|       |:|||:|.||::|||:||::|||||||||||||:||.... |
Zfish    13 VAADSSGS--SFSITANLLQLSKHIKYENLAAGLAGGVISTMVLHPLDLIKIRFAVSDGLKMR-P 74

  Fly    62 QYRGLSSAFTTIFRQEGFRGLYKGVTPNVWGSGSSWGLYFMFYNTIKTFIQGGNTTMPLGPTMNM 126
            ||.|:.....||::.||.||||:|||||:||:||||||||:|||.||.:.|.|..| .|....::
Zfish    75 QYDGMLDCMKTIWKLEGIRGLYQGVTPNIWGAGSSWGLYFLFYNAIKAYTQEGRQT-ELSACEHL 138

  Fly   127 LAAAESGILTLLLTNPIWVVKTRLCLQCDA-ASSAEYRGMIHALGQIYKEEGIRGLYRGFVPGML 190
            ::|||:|||||.||||:||.||||.||.:| .|..:|:||:.||.:||:.|||.|||||||||::
Zfish   139 VSAAEAGILTLCLTNPVWVTKTRLVLQYNADPSRKQYKGMMDALVKIYRHEGIPGLYRGFVPGLV 203

  Fly   191 GVSHGAIQFMTYEELKNAYNEYRKLPIDTKLATTEYLAFAAVSKLIAAAATYPYQVVRARLQDHH 255
            |.||.|:||||||.||...|:.:|:|.::.|:..||:|.||:||:.|.|.|||||||||||||.|
Zfish   204 GTSHAALQFMTYEGLKREQNKCKKMPSESLLSPLEYIAIAAISKIFAVAVTYPYQVVRARLQDQH 268

  Fly   256 HRYNGTWDCIKQTWRFEGYRGFYKGLKASLTRVVPACMVTFLVYENVSHFLL 307
            :.|:|..|.:::||..||..|||||:..:|.||:|||.:||||:||||..||
Zfish   269 NNYSGIVDVMRRTWSNEGVEGFYKGMVPNLVRVIPACCITFLVFENVSRLLL 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8026	NP_724769.2	PTZ00169	13..287	CDD:240302	158/281 (56%)
		Mito_carr	23..115	CDD:278578	58/91 (64%)
		Mito_carr	119..213	CDD:278578	55/94 (59%)
		Mito_carr	220..307	CDD:278578	50/86 (58%)
slc25a32a	NP_956550.1	Mito_carr	37..123	CDD:278578	57/86 (66%)
		Mito_carr	131..220	CDD:278578	53/88 (60%)
		Mito_carr	234..323	CDD:278578	52/87 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581531
Domainoid	1	1.000	126	1.000	Domainoid score	I5352
eggNOG	1	0.900	-	-		E1_KOG0764
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6151
Inparanoid	1	1.050	356	1.000	Inparanoid score	I2203
OMA	1	1.010	-	-		QHG53601
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002021
OrthoInspector	1	1.000	-	-		otm26606
orthoMCL	1	0.900	-	-		OOG6_100767
Panther	1	1.100	-	-	O	PTHR45683
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1725
SonicParanoid	1	1.000	-	-		X1155
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.790