DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8026 and Slc25a32

DIOPT Version :9

Sequence 1:	NP_724769.2	Gene:	CG8026 / 35941	FlyBaseID:	FBgn0033391	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001166805.1	Gene:	Slc25a32 / 315023	RGDID:	1565789	Length:	316	Species:	Rattus norvegicus

Alignment Length:	309	Identity:	177/309 - (57%)
Similarity:	223/309 - (72%)	Gaps:	7/309 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 STGSPKKFNVFAHVKYEHLVAGVSGGVVSTLILHPLDLIKIRFAVNDGRTATVPQYRGLSSAFTT 72
            :.||.....||.||:||:|||||||||:|.|.||||||:||||||:||.... |:|:|:.....|
  Rat     8 AAGSAAWSAVFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLEVR-PKYKGILHCLAT 71

  Fly    73 IFRQEGFRGLYKGVTPNVWGSGSSWGLYFMFYNTIKTFIQGGNTTMPLGPTMNMLAAAESGILTL 137
            |::.:|.||||:||||||||:|.||||||.|||.||::...|.... |.....:::|||:|.:||
  Rat    72 IWKVDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAEQ-LEALEYLISAAEAGAMTL 135

  Fly   138 LLTNPIWVVKTRLCLQCDAA---SSAEYRGMIHALGQIYKEEGIRGLYRGFVPGMLGVSHGAIQF 199
            .:|||:||.||||.||....   |..:|:|||.||.:|||.||:||||:|||||:.|.||||:||
  Rat   136 CITNPLWVTKTRLMLQYGGVVNPSQRQYKGMIDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQF 200

  Fly   200 MTYEELKNAYNEY-RKLPIDTKLATTEYLAFAAVSKLIAAAATYPYQVVRARLQDHHHRYNGTWD 263
            |.||.||..||:: .||| :.:|:|.||::.||:||:.|.|||||||||||||||.|..|.|..|
  Rat   201 MAYEVLKLKYNKHINKLP-EAQLSTAEYISVAALSKIFAVAATYPYQVVRARLQDQHVSYGGVTD 264

  Fly   264 CIKQTWRFEGYRGFYKGLKASLTRVVPACMVTFLVYENVSHFLLARRKR 312
            .|.:|||.||..|||||:..:|.||.|||.:||:|||||||||...|::
  Rat   265 VITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENVSHFLYDLREK 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8026	NP_724769.2	PTZ00169	13..287	CDD:240302	158/277 (57%)
		Mito_carr	23..115	CDD:278578	57/91 (63%)
		Mito_carr	119..213	CDD:278578	53/97 (55%)
		Mito_carr	220..307	CDD:278578	55/86 (64%)
Slc25a32	NP_001166805.1	PTZ00169	26..307	CDD:240302	166/283 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341526
Domainoid	1	1.000	122	1.000	Domainoid score	I5540
eggNOG	1	0.900	-	-		E1_KOG0764
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6151
Inparanoid	1	1.050	347	1.000	Inparanoid score	I2234
OMA	1	1.010	-	-		QHG53601
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002021
OrthoInspector	1	1.000	-	-		oto96388
orthoMCL	1	0.900	-	-		OOG6_100767
Panther	1	1.100	-	-	LDO	PTHR45683
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1155
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760